Feasibility of Intraneural Auditory Prosthesis Stimulating Electrode Array

神经内听觉假体刺激电极阵列的可行性

• 批准号: 7576065
• 金额: $ 73.83万
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-03-01 至 2009-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7576065
• 关键词: Feasibility; Intraneural; Auditory; Prosthesis; Stimulating

The objective of this research is to determine the feasibility of intraneural, auditory nerve stimulating electrode arrays that could lead to the development of improved human multichannel auditory prostheses. This project will study the feasibility of intraneural, auditory nerve stimulating electrode arrays, utilize neurophysiological tests to evaluate them acutely in an animal model, implant the arrays chronically and stimulate them in the animal model, evaluate any possible histopathology resulting from implantation or stimulation of the tissue. Based on these studies, the offer will make a recommendation as to whether further studies should be pursued to develop an actual human intraneural electrode array.

本研究的目的是确定神经内听觉神经刺激电极阵列的可行性，这可能会导致改进的人类多通道听觉假体的发展。本项目将研究神经内听觉神经刺激电极阵列的可行性，利用神经生理学测试在动物模型中对其进行急性评估，在动物模型中长期植入阵列并刺激它们，评估植入或刺激组织可能导致的任何组织病理学。基于这些研究，该提议将建议是否应进行进一步研究以开发实际的人体神经内电极阵列。