EFFECTIVE ROOM TEMPERATURE DENTAL HANDPIECE STERILIZER

有效室温牙科手机消毒器

• 批准号: 7668614
• 负责人: CZESLAW GOLKOWSKI
• 金额: $ 40.44万
• 依托单位: SUPER PULSE
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-12 至 2011-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7668614
• 关键词: Achievement; Adverse effects; Air; Chemicals; Corrosives; Dental; Dental Care; Dental Equipment; Dental Handpieces; Dental Offices; Dentists; Deposition; Development; Devices; Elements; Free Radicals; Gases; Goals; Heating; High temperature of physical object; Life; Maintenance; Manufacturer Name; Marketing; Metals; Methods; Operative Surgical Procedures; Patients; Performance; Phase; Process; Production; Quality of Care; Reproduction spores; Research; Risk; Source; Steam; Sterility; Sterilization for infection control; Stream; Surface; System; Technology; Temperature; Testing; Time; United States Food and Drug Administration; Work; base; cold temperature; cost; design; disease transmission; follow-up; instrument; killings; microorganism; novel; novel strategies; programs; prototype; purge; tool

DESCRIPTION (provided by applicant): We propose to research and develop a novel, reliable, and affordable technology for effective sterilization of Dental Handpieces (DH) at room temperature. The Food and Drug Administration (FDA) recommends that these delicate instruments be heat- sterilized between patients to reduce the risk of disease transmission. While autoclaving is the most versatile of these methods, many materials and instruments suffer irreversible damage when exposed to moist heat at the temperatures and for the times required for sterilization. After several sterilization cycles, moist heat shortens the useful life of most Dental tools. Moist heat sterilization rapidly corrodes metal instruments and dulls blades. The technology utilizes a non-corrosive gas sterilant produced in a free radical source to sterilize a wide range of materials and surfaces. The air/gas stream containing free radicals produced in the source will even be able to penetrate and efficiently sterilize instruments such as handpiece inner channels. The proposed sterilization technology is safe, will not require chemicals, and will be simple in operation and maintenance free. Its simplicity and affordability resulting from operating at low-temperature and with low energy requirements make it very suitable for developing a sterilization device for use in many Dental offices. During Phase I tests, an air stream containing free radicals produced in the source system effectively inactivated 100% of highly concentrated microorganisms in spore form deposited inside the narrowest DH channel at the temperature of the sterilization process maintained below 30oC in time less than 10 minutes. During Phase I of the program, material compatibility were assessed and proved that the technology is safe for DH. .High quality care at lowest possible cost creates a necessity of development of new safe, cheap sterilization technologies. Sterilization of Dental Handpieces (DHs), is currently one of the important issues in Dental care, since these precision instruments, costing about $1,000 each, need to be sterilized between patients. The proposed development of the effective, room temperature sterilization technology offers cheap alternative to autoclaving.

描述（由申请人提供）：我们建议研究和开发一种新型、可靠且经济实惠的技术，用于在室温下对牙科手机（DH）进行有效灭菌。美国食品和药物管理局（FDA）建议，这些精致的仪器在患者之间进行热消毒，以减少疾病传播的风险。虽然高压灭菌是这些方法中最通用的方法，但许多材料和器械在灭菌所需的温度和时间下暴露于湿热时会遭受不可逆的损坏。经过几个消毒周期，湿热缩短了大多数牙科工具的使用寿命。湿热灭菌会迅速腐蚀金属器械并使刀片变钝。该技术利用在自由基源中产生的非腐蚀性气体灭菌剂对各种材料和表面进行灭菌。在源中产生的含有自由基的空气/气体流甚至将能够穿透并有效地对诸如手持件内部通道的器械进行灭菌。拟议的灭菌技术是安全的，不需要化学品，操作简单，无需维护。它的简单性和可承受性导致在低温和低能量要求下操作，使其非常适合开发用于许多牙科诊所的灭菌设备。在第一阶段的测试中，在源系统中产生的含有自由基的空气流有效地灭活了100%的高度浓缩的微生物，这些微生物以孢子的形式沉积在Westwest DH通道内，灭菌过程的温度保持在30 ℃以下，时间少于10分钟。在项目的第一阶段，对材料兼容性进行了评估，证明该技术对DH是安全的。以尽可能低的成本提供高质量的护理，这就需要开发新的安全、廉价的消毒技术。牙科手机（DH）的灭菌是目前牙科护理中的重要问题之一，因为这些精密仪器，每个成本约为1，000美元，需要在患者之间进行灭菌。提出的有效的室温灭菌技术的发展提供了廉价的替代高压灭菌。