EFFECTIVE ROOM TEMPERATURE DENTAL HANDPIECE STERILIZER

有效室温牙科手机消毒器

• 批准号: 7154561
• 负责人: CZESLAW GOLKOWSKI
• 金额: $ 10万
• 依托单位: SUPER PULSE
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-12 至 2007-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7154561
• 关键词: blood; heat; metals; plasma; spores; temperature

DESCRIPTION (provided by applicant): Project Summary/Abstract: We propose to research and develop a novel, reliable, and affordable technology for effective sterilization of dental handpieces at room temperature. The Food and Drug Administration (FDA) recommends that these delicate instruments be heat-sterilized between patients to reduce the risk of disease transmission. While autoclaving is the most versatile of these methods, many materials and instruments suffer irreversible damage when exposed to moist heat at the temperatures and for the times required for sterilization. After several sterilization cycles, moist heat shortens the useful life of most dental tools. Moist heat sterilization rapidly corrodes metal instruments and dulls blades. The technology utilizes a non-corrosive gas sterilant produced in a non-thermal plasma source powered by a standard microwave oven magnetron to sterilize a wide range of materials and surfaces. The air/gas stream containing free radicals produced in the non- thermal plasma source will even be able to penetrate and efficiently sterilize instruments such as handpiece inner channels. The proposed sterilization technology is safe, will not require chemicals, and will be simple in operation and maintenance free. Its simplicity and affordability resulting from operating at low-moisture, low-temperature and with low energy requirements make it very suitable for developing a sterilization device for use in many dental offices. During preliminary tests, an air stream containing free radicals produced in the Pulsed Microwave Non-thermal Plasma (PMNP) system effectively inactivated 100% of highly concentrated microorganisms (107/ml) deposited on a Petri dish and killed 106 spores imbedded in a small paper disk with the temperature of the sterilization process maintained at~30oC. During Phase I of the program, preliminary material compatibility will be assessed and tests of sterilizing efficacy of dental reusable instruments including dental handpiece inner channels will be validated. Project Narrative: High quality care at lowest possible cost creates a necessity of development of new cheap sterilization technologies. Sterilization of Dental Handpieces (DHs) is currently 1 of the important issues in dental care, since these precision instruments, costing about $800.00 each, need to be sterilized between patients. The proposed development of the effective, room temperature sterilization technology offers a cheap alternative to autoclaving.

描述（由申请人提供）：项目总结/摘要：我们建议研究和开发一种新颖、可靠且经济实惠的技术，用于在室温下对牙科手机进行有效灭菌。美国食品和药物管理局（FDA）建议这些精密仪器在患者之间进行热消毒，以降低疾病传播的风险。虽然高压灭菌是这些方法中最通用的方法，但许多材料和器械在灭菌所需的温度和时间下暴露于湿热时会遭受不可逆的损坏。经过几个消毒周期，湿热缩短了大多数牙科工具的使用寿命。湿热灭菌会迅速腐蚀金属器械并使刀片变钝。该技术利用由标准微波炉磁控管供电的非热等离子体源产生的非腐蚀性气体灭菌剂对各种材料和表面进行灭菌。包含在非热等离子体源中产生的自由基的空气/气体流甚至将能够穿透诸如手持件内部通道的器械并对其进行有效灭菌。拟议的灭菌技术是安全的，不需要化学品，操作简单，无需维护。由于在低湿度、低温和低能量要求下操作，其简单性和经济性使其非常适合开发用于许多牙科诊所的灭菌设备。在初步测试中，脉冲微波非热等离子体（PMNP）系统产生的含有自由基的气流有效地灭活了培养皿上沉积的100%高浓度微生物（107/ml），并杀死了嵌入小纸片中的106个孢子。灭菌过程的温度保持在~ 30 ° C。在项目的第一阶段，将评估初步材料兼容性，并对牙科可重复使用器械（包括牙科手机内通道）的灭菌效果进行验证。项目叙述：以尽可能低的成本提供高质量的护理，因此有必要开发新的廉价灭菌技术。牙科手机（DH）的灭菌是目前牙科护理中的重要问题之一，因为这些精密仪器，每个成本约为800美元，需要在患者之间进行灭菌。拟议的有效的室温灭菌技术的发展提供了一个廉价的替代高压灭菌。