A Novel Handheld Three-Dimensional Camera for Wound Healing Monitoring

描述（由申请人提供）：我们提出了这个第二阶段SBIR计划，以进一步利用我们第一阶段努力的非常有前途的结果，开发一种新型的手持式三维（3D）相机，能够对伤口的大小、形状、体积、颜色和愈合状态进行客观、定量和真实的3D测量。伤口愈合的准确测量使临床医生能够评估、记录、改进和个性化给予每个伤口患者的治疗计划。在目前的伤口护理实践中，临床医生经常目视检查伤口以评估愈合状态。这不是最佳实践，因为人类视觉缺乏精确性和一致性，并且量化缓慢或微妙的变化非常困难。因此，量化皮肤颜色和几何形状变化的仪器在帮助临床医生评估愈合状态和判断充血、血肿、局部炎症、继发感染和组织坏死的影响方面特别有用。我们在SBIR计划下开发的手持式3D摄像机将证明自己比传统的伤口护理监测方法具有几个独特的优势，包括： 非接触式测量：没有污染伤口部位或干扰恢复组织的风险。 快速且易于用途：在几分之一秒内获取单个图像，并自动将多个3D图像真实的实时合并为完整的伤口3D模型;适用于医院和家庭护理/远程医疗应用。 高精度：亚毫米级精度和最佳景深，确保准确捕捉到暗示愈合的变化，并将伪影降至最低。 定量测量：2D颜色和3D形状都提供了伤口参数的定量数字测量，例如面积大小、体积、长度、深度、表面粗糙度及其轮廓。 手持设备：它不仅是一个方便的便携式仪器，它还提供了一个独特的能力，以测量伤口周围的四肢延伸，并不能完全从一个位置可见。 大规模商业市场的合理成本：所提出的手持式3D相机设计导致廉价的生产。我们的目标价格为这样一个系统在大规模生产是在1000美元以下。如果成功的话，预计该手持式3D相机产品将在临床、家庭护理和远程医疗应用中具有巨大的市场潜力。

DESCRIPTION (provided by applicant): We propose this Phase II SBIR program to further capitalize on the very promising results from our Phase I effort to develop a novel, handheld three-dimensional (3D) camera able to perform objective, quantitative, and true 3D measurements of the size, shape, volume, color, and healing status of wounds. Accurate measurement of wound healing enables clinicians to assess, document, improve, and individualize the treatment plan given to each wound patient. In current wound care practices, clinicians often visually inspect the wound to evaluate the healing status. This is not an optimal practice because human vision lacks precision and consistency, and quantifying slow or subtle changes is very difficult. As a result, an instrument that quantifies both skin color and geometric shape variations would be particularly useful in helping clinicians assess healing status and judge the effect of hyperemia, hematoma, local inflammation, secondary infection, and tissue necrosis. Our handheld 3D camera developed under this SBIR program will prove itself to have several unique advantages over traditional methods for monitoring wound care, to include: Non-contact measurement: No risk of contaminating the wound site or disturbing the recovering tissue. Fast and easy to use: Acquires a single image in a fraction of a second and automatically merges multiple 3D images into a complete 3D model of the wound in real time; suitable for both hospital and homecare/telemedicine applications. High Accuracy: Sub-millimeter accuracy with optimal depth of field to ensure that changes suggestive of healing are captured precisely and with minimal artifact. Quantitative measurements: Both 2D color and 3D shape provide quantitative digital measurements of wound parameters such as area size, volume, length, depth, surface roughness, and its profile. Handheld device: Not only is it a handy portable instrument, it also provides a unique ability to measure wounds that extend around limbs and that are not fully visible from a single position. Reasonable cost for mass commercial market: The proposed handheld 3D camera design leads to inexpensive production. Our targeted price for such a system in mass production is under $1,000. The proposed handheld 3D camera product, if successful, is expected to have tremendous market potential in clinical, homecare, and telemedicine applications.