课题基金 / 基金详情

DYNAMICS, FUNCTION, AND STABILITY ON VANX

DYNAMICS, FUNCTION, AND STABILITY ON VANX
VANX 的动态、功能和稳定性
批准号:
7598732
负责人:
JOSEPH P LORIA
金额:
$0.05万
依托单位国家:
美国
项目类别:
财政年份:
2007
资助国家:
美国
项目状态:
已结题
起止时间:
2007-03-01 至 2008-02-29

项目摘要

项目成果

JOSEPH P LORIA的其他基金

相关文献

中文摘要
翻译
这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金, 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 VanX是一种含锌的D-丙氨酸-D-丙氨酸二肽酶。VanX识别一类化学上很窄的底物。通过拟议的实验,我将了解这种酶如何区别于替代底物,即使它们在结构上是相关的。
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. VanX is a zinc-containing D-Ala-D-Ala dipeptidase. VanX recognizes a chemically narrow class of substrates. Through the proposed experiments, I am to understand how this enzyme discriminates against alternative substrates even when they are structurally related.
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会议论文
Investigating the relationship between allostery and substrate specificity in protein tyrosine phosphatases
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  • 财政年份:
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NMR dynamical characterization of WT and cancer-associated DNA polymerase
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