MONTE CARLO ALGORITHM FOR VIRUS PARTICLE RECONSTRUCTION

病毒粒子重建的蒙特卡罗算法

• 批准号: 7598576
• 负责人: WEN JIANG
• 金额: $ 1.63万
• 依托单位: BAYLOR COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-12-01 至 2007-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7598576
• 关键词: Algorithms; Computer Retrieval of Information on Scientific Projects Database; Computer software; Funding; Grant; Institution; Research; Research Personnel; Resolution; Resources; Source; Structure; United States National Institutes of Health; Virion; improved; nanometer; particle; reconstruction

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The SAVR software package was developed for icosahedral virus particle reconstruction. This software has sucessfully solved several virus particle structures to sub-nanometer resolution. Continuous improvements are being made to make it more robust and universal. We are exploring the use of Monte Carlo algorithm to improve the efficiency and accuracy of the particle orientation search and refinement.

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