BIOMOLECULAR INTERACTION AND GENE NETWORK SIMULATIONS

生物分子相互作用和基因网络模拟

• 批准号: 7601336
• 负责人: YIANNIS KAZNESSIS
• 金额: $ 0.03万
• 依托单位: CARNEGIE-MELLON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-08-01 至 2008-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7601336
• 关键词: Award; Computer Retrieval of Information on Scientific Projects Database; Funding; Grant; Institution; Request for Proposals; Research; Research Personnel; Resources; Source; Synthetic Genes; System; United States National Institutes of Health; Work; antimicrobial peptide; design; gene interaction; insight; molecular dynamics; simulation

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. In the current proposal, we are requesting allocations for two different projects. 1. Insights into the mechanism of action of antimicrobial peptides from molecular dynamics simulations. This is a continuation of proposed work awarded with AAB resources in 2003, and NRAC resources in 2004 and 2005. We describe the results of the work so far, and the new systems we will investigate. 2. Design and simulations of artificial gene networks. This is a continuation of proposed work awarded with NRAC resources in 2004 and 2005.

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 在目前的提案中，我们请求为两个不同的项目分配资金。1.分子动力学模拟研究抗菌肽的作用机理。这是2003年授予AAB资源、2004年和2005年授予NRAC资源的拟议工作的延续。我们描述了到目前为止工作的结果，以及我们将调查的新系统。2.人工基因网络的设计与仿真。这是2004年和2005年授予NRAC资源的拟议工作的继续。