SHEDDING LIGHT ON THE MECHANISM OF POTENTIALS TUNING IN BIOLOGICAL REDOX CENTER

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 氢键在从生物到表面和超分子化学的众多领域中扮演着重要的角色。术语“氢键”是指具有各种共价和极性贡献的广泛相互作用。特别是，氢键在多肽和核酸的折叠和包装中起着重要的作用。最近的研究也指出了氢键在第二壳层相互作用、金属结合和金属蛋白的选择性以及控制膜蛋白动力学方面的重要性。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Hydrogen bonds play an important role in an overwhelming variety of fields from biology to surface and supramolecular chemistry. The term "hydrogen bond" refers to a wide range of interactions with various covalent and polar contributions. In particular, hydrogen bonds have an important role in the folding and packing of peptides and nucleic acids. Recent studies also point to the importance of hydrogen bonding in the context of second-shell interactions, in metal binding and selectivity in metalloproteins, and in controlling the dynamics of membrane proteins.