SHEDDING LIGHT ON THE MECHANISM OF POTENTIALS TUNING IN BIOLOGICAL REDOX CENTER

揭示生物氧化还原中心电位调节机制

• 批准号: 7955224
• 负责人: AVIGDOR SCHERZ
• 金额: $ 0.64万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-05-01 至 2010-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7955224
• 关键词: Binding; Biological; Biology; Biomedical Computing; Chemistry; Computer Retrieval of Information on Scientific Projects Database; Funding; Grant; Hydrogen Bonding; Institution; Light; Membrane Proteins; Metalloproteins; Metals; Oxidation-Reduction; Peptide Nucleic Acids; Play; Research; Research Personnel; Resources; Role; Source; Surface; United States National Institutes of Health

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Hydrogen bonds play an important role in an overwhelming variety of fields from biology to surface and supramolecular chemistry. The term "hydrogen bond" refers to a wide range of interactions with various covalent and polar contributions. In particular, hydrogen bonds have an important role in the folding and packing of peptides and nucleic acids. Recent studies also point to the importance of hydrogen bonding in the context of second-shell interactions, in metal binding and selectivity in metalloproteins, and in controlling the dynamics of membrane proteins.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 氢键在从生物学到表面和超分子的众多领域中发挥着重要作用 化学.术语“氢键”是指具有各种共价和极性贡献的广泛的相互作用。 特别地，氢键在肽和核酸的折叠和包装中具有重要作用。最近 研究还指出了氢键在第二层相互作用、金属结合和 金属蛋白的选择性，以及控制膜蛋白的动力学。