IDENTIFICATION OF PROTEINS THAT INTERACT WITH THE EXOCYST COMPLEX

与外囊复合物相互作用的蛋白质的鉴定

• 批准号: 7602219
• 负责人: PETER Jay NOVICK
• 金额: $ 0.08万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-09-01 至 2008-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7602219
• 关键词: Complex; Computer Retrieval of Information on Scientific Projects Database; Funding; Grant; Institution; Membrane Protein Traffic; Numbers; Pathway interactions; Proteins; Research; Research Personnel; Resources; Source; Staging; United States National Institutes of Health; Yeasts

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We have recently isolated a complex, known as the exocyst, which is required for the final stage of membrane traffic on the yeast secretory pathway. While the 8 components of the complex were identified a few years ago, it is clear that a number of additional proteins interact with the exocyst complex to control its assembly or function.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 我们最近分离出一种称为外囊的复合物，它是酵母分泌途径膜运输的最后阶段所必需的。 虽然该复合物的 8 个成分在几年前就被鉴定出来，但很明显，许多其他蛋白质与外囊复合物相互作用以控制其组装或功能。