250K PARTICLE PROJECT

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This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. In this project we demonstrated the potential of the Leginon system for high-throughput data acquisition by performing an experiment in which we acquired images of more than 280,000 particles of GroEL in a single twenty-five hour session at the microscope.