ADMINISTRATIVE CORE

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A. INTRODUCTION As required by this RFA, the proposed Fragile X Research Center grant is submitted as a supplement to the P30 Mental Retardation and Developmental Disabilities Research Center at the University of North Carolina at Chapel Hill, Joe Piven, MD, Principal Investigator. Also as required, a separate administrative core is proposed in support of the Fragile X Center grant. Dr. Don Bailey will serve as the Fragile X Center Director, Associate Director of Fragile X Research for the North Carolina MRDDRC, and Director of the Administrative Core. Dr. Debra Skinner will serve as Associate Director of the Administrative Core. Dr. Bailey has been the Fragile X Center director on our current Fragile X Center and Dr. Skinner has been an investigator affiliated with the center and co-director of the current center's Data Collection Core. The Administrative Core will manage the daily operations of the Fragile X Center, facilitate linkages and integration across projects, and coordinate communications with the NICHD and with the other funded Fragile X Centers. The core will also ensure that the aims of the research projects are carried out by the research project leaders and that support cores provide the necessary services to further the research aims. To accomplish these aims, the core will be responsible for five major activities.