ACTG A5164(V 20)-ANTIRETROVIRAL THERAPY FOR HIV-INFECTED ADULTS W/ACUTE OIS

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This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The objective of this study to learn whether it is better to start drugs that fight HIV right away, while a patient are being treated for an OI(opportunistic infection) or BI(bacterial infection), or wait until after the OI or BI has been treated. It is not known whether the HIV drugs cause side effects that could worsen the problems for seriously ill people such as those with OI or BI. Another purpose of this study is to compare the safety and effectiveness of the HIV drugs when started during or after an OI or BI. The purpose of the substudy is to compare the levels of some of the HIV drugs in the blood while a patient is receiving treatment for a respiratory infection and after they have stopped treatment for the respiratory infection.