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CYP2B6 GENOTYPE-PHENOTYPE AND THE INFLUENCE OF SEX AND ETHNICITY

CYP2B6 GENOTYPE-PHENOTYPE AND THE INFLUENCE OF SEX AND ETHNICITY
CYP2B6 基因型-表型以及性别和种族的影响
批准号：
7625648
负责人：
CELESTE M LINDLEY
金额：
$5.55万
依托单位：
UNIV OF NORTH CAROLINA CHAPEL HILL
依托单位国家：
美国
项目类别：
财政年份：
2006
资助国家：
美国
项目状态：
已结题
起止时间：
2006-12-01 至 2007-11-30
来源：
https://reporter.nih.gov/project-details/7625648
关键词：
AffectComputer Retrieval of Information on Scientific Projects DatabaseEthnic OriginFundingGenotypeGrantInstitutionLearningLiverPharmaceutical PreparationsPhenotypePurposeRaceResearchResearch PersonnelResourcesSourceUnited States National Institutes of Healthenzyme activityhuman CYP2B6 proteinresearch studysex

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中文摘要
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英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this research study is to learn how sex and race/ethnicity affect the activity of an enzyme in your liver that breaks down drugs called cytochrome P450 2B6 (CYP2B6).
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会议论文
LCCC 0424: PHASE I ERLOTINIB GIVEN EVERY 72 HOURS TO PATIENTS WITH GLIOBLASTOMA
EVALUATING THE EFFECT OF APREPITANT ON CYCLOPHOSPHAMIDE PHARMACOKINETICS
LCCC 0424: PHASE I ERLOTINIB GIVEN EVERY 72 HOURS TO PATIENTS WITH GLIOBLASTOMA
VALIDATING BUPROPION AS AN IN VIVO PROBE FOR HUMAN CYTOCHROME P450 2B6