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MLN8054, AURORA A KINASE INHIBITOR IN PATIENTS WITH ADVANCED SOLID TUMOR

MLN8054, AURORA A KINASE INHIBITOR IN PATIENTS WITH ADVANCED SOLID TUMOR
MLN8054，AURORA 一种用于晚期实体瘤患者的激酶抑制剂
批准号：
7625646
负责人：
ELIZABETH CLAIRE DEES
金额：
$0.08万
依托单位：
UNIV OF NORTH CAROLINA CHAPEL HILL
依托单位国家：
美国
项目类别：
财政年份：
2006
资助国家：
美国
项目状态：
已结题
起止时间：
2006-12-01 至 2007-11-30
来源：
https://reporter.nih.gov/project-details/7625646
关键词：
Antineoplastic AgentsBlood TestsComputer Retrieval of Information on Scientific Projects DatabaseDoseFundingGoalsGrantInstitutionMalignant NeoplasmsPatientsPharmaceutical PreparationsRefractoryResearchResearch PersonnelResourcesSkin NeoplasmsSolid NeoplasmSourceTumor TissueUnited States National Institutes of Healthkinase inhibitor

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中文摘要
翻译
这个子项目是众多研究子项目之一
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The primary goal of this study is to determine the safe dose of the new anti-cancer drug, MLN8054, in patients with refractory cancers. This will be done through a dose escalation study. Secondary aims are to look at markers of this drug's activity in the skin and tumor tissue, as well as evaluate the clearance of MLN804 through blood tests.
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