COBRE: UID: STRUCTURAL BIOLOGY CORE FACILITY

COBRE：UID：结构生物学核心设施

• 批准号: 7720641
• 负责人: Gary W Daughdrill
• 金额: $ 0.65万
• 依托单位: UNIVERSITY OF IDAHO
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-05-15 至 2009-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7720641
• 关键词: Administrator; Biochemistry; Centers of Research Excellence; Computer Retrieval of Information on Scientific Projects Database; Core Facility; Crystallography; Equipment; Funding; Future; Grant; Idaho; Individual; Institution; Microbiology; Molecular Biology; Protein Dynamics; Proteins; Range; Research; Research Personnel; Resources; Secure; Solutions; Source; Structure; System; United States National Institutes of Health; Universities; Washington; digital; interest; pathogen; structural biology

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The University of Idaho Structural Biology Core Facility is currently available for users statewide via remote access using a secure, encrypted interface developed by the IBEST system administrator, Ken Blair. This facility is comprised of a 600 MHz digital NMR spectrometer capable of characterizing the solution state structure and dynamics of proteins in the range of 40 KDa. In the last year, Dr. Daughdrill has served as director of the facility and remains the primary user. Other users included, Drs. Doug Cole and Andrzej Paszcynski from the Department of Microbiology, Molecular Biology and Biochemistry at the University of Idaho, and Dr. Steve Alam of Washington State University. Individuals at other universities have expressed interest in using the facility, including Dr. Julia Oxford and Dr. Susan Shadle of Boise State University. Future plans for the facility involve expansion to include equipment for protein crystallography, pending renewal of the Host-Pathogen Interaction COBRE (PI: Dr. Gregory Bohach).

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 爱达荷大学结构生物学核心设施目前可通过远程访问使用由IBEST系统管理员Ken Blair开发的安全，加密的界面，可通过远程访问为用户提供。 该设施由600 MHz数字NMR光谱仪组成，能够表征40 kDa范围内蛋白质的溶液状态结构和动力学。 去年，Daughdrill博士曾担任该设施的主任，并且仍然是主要用户。 包括其他用户，Drs。爱达荷大学微生物，分子生物学和生物化学系的道格·科尔（Doug Cole）和安德烈·帕斯辛（Andrzej Passcynski）以及华盛顿州立大学的史蒂夫·阿拉姆（Steve Alam）博士。 其他大学的个人表示有兴趣使用该设施，包括朱莉娅·牛津博士和博伊西州立大学的苏珊·萨德尔博士。该设施的未来计划涉及扩展，包括用于蛋白质晶体学的设备，即将续签宿主 - 病原体相互作用柯布雷（PI：Gregory Bohach博士）。