COBRE: UID: STRUCTURAL BIOLOGY CORE FACILITY

COBRE：UID：结构生物学核心设施

• 批准号: 7381302
• 负责人: Gary W Daughdrill
• 金额: $ 0.69万
• 依托单位: UNIVERSITY OF IDAHO
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-02-01 至 2007-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7381302
• 关键词: COBRE; UID; STRUCTURAL; BIOLOGY; CORE

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The University of Idaho Structural Biology Core Facility is currently available for users statewide via remote access using a secure, encrypted interface developed by the IBEST system administrator, Ken Blair. This facility is comprised of a 600 MHz digital NMR spectrometer capable of characterizing the solution state structure and dynamics of proteins in the range of 40 KDa. In the last year, Dr. Daughdrill has served as director of the facility and remains the primary user. Other users included, Drs. Doug Cole and Andrzej Paszcynski from the Department of Microbiology, Molecular Biology and Biochemistry at the University of Idaho, and Dr. Steve Alam of Washington State University. Individuals at other universities have expressed interest in using the facility, including Dr. Julia Oxford and Dr. Susan Shadle of Boise State University. Future plans for the facility involve expansion to include equipment for protein crystallography, pending renewal of the Host-Pathogen Interaction COBRE (PI: Dr. Gregory Bohach).

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。爱达荷大学结构生物学核心设施目前可供全州用户通过使用IBEST系统管理员Ken Blair开发的安全加密界面进行远程访问。该设备由600 MHz数字核磁共振波谱仪组成，能够表征40 KDa范围内蛋白质的溶液状态、结构和动力学。在过去的一年里，道德里克博士一直担任该设施的负责人，目前仍是该设施的主要用户。其他用户包括爱达荷大学微生物学、分子生物学和生物化学系的Doug Cole博士和Andrzej Paszcynski博士，以及华盛顿州立大学的Steve Alam博士。其他大学的个人也表达了使用该设施的兴趣，包括博伊西州立大学的朱莉娅·牛津博士和苏珊·沙德尔博士。该设施的未来计划包括扩建，包括蛋白质结晶学设备，等待宿主-病原体相互作用Cobre的更新(PI：Gregory Bohach博士)。