COBRE: UID: STRUCTURAL BIOLOGY CORE FACILITY

COBRE：UID：结构生物学核心设施

• 批准号: 7381302
• 负责人: Gary W Daughdrill
• 金额: $ 0.69万
• 依托单位: UNIVERSITY OF IDAHO
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-02-01 至 2007-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7381302
• 关键词: COBRE; UID; STRUCTURAL; BIOLOGY; CORE

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The University of Idaho Structural Biology Core Facility is currently available for users statewide via remote access using a secure, encrypted interface developed by the IBEST system administrator, Ken Blair. This facility is comprised of a 600 MHz digital NMR spectrometer capable of characterizing the solution state structure and dynamics of proteins in the range of 40 KDa. In the last year, Dr. Daughdrill has served as director of the facility and remains the primary user. Other users included, Drs. Doug Cole and Andrzej Paszcynski from the Department of Microbiology, Molecular Biology and Biochemistry at the University of Idaho, and Dr. Steve Alam of Washington State University. Individuals at other universities have expressed interest in using the facility, including Dr. Julia Oxford and Dr. Susan Shadle of Boise State University. Future plans for the facility involve expansion to include equipment for protein crystallography, pending renewal of the Host-Pathogen Interaction COBRE (PI: Dr. Gregory Bohach).

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。爱达荷州结构生物学核心设施的大学目前可供全州用户通过远程访问使用的安全，加密的界面开发的IBEST系统管理员，肯布莱尔。该设施由一台600 MHz数字NMR光谱仪组成，能够在40 KDa范围内表征蛋白质的溶液状态结构和动力学。去年，Daughdrill博士担任该设施的主任，仍然是主要用户。其他用户包括爱达荷州大学微生物学、分子生物学和生物化学系的Doug科尔和Andrzej Paszcynski博士以及华盛顿州立大学的Steve Alam博士。其他大学的个人也表示有兴趣使用该设施，包括博伊西州立大学的朱莉娅·牛津博士和苏珊·沙德尔博士。该设施的未来计划涉及扩展，包括蛋白质晶体学设备，等待更新宿主-病原体相互作用COBRE（PI：Gregory Bohach博士）。