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Small Imaging Core

小型成像核心

基本信息

批准号：
7728535
负责人：
Joel Richard Garbow
金额：
$ 0.51万
依托单位：
WASHINGTON UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2008
资助国家：
美国
起止时间：
2008-09-24 至 2013-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7728535
关键词：
Academic Medical Centers Animal Model Animals Arts Biological Models Bioluminescence Biometry Cancer Model Catheters Communities Compatible Consultations Contrast Media Custom Data Data Analyses Development Engineering Fluorescence Funding Heart Image Image Analysis Imagery Imaging technology Informatics Institution Laboratories Laboratory Animals Magnetic Resonance Imaging Maintenance Malignant Neoplasms Methods Microscopy Modality Mus Operative Surgical Procedures Optics Physics Physiologic Monitoring Placement Positron-Emission Tomography Procedures Rattus Research Research Infrastructure Research Personnel Resource Development Resources Scientist Services System Technology Universities Validation Washington absorption design diffuse optical tomography frontier in vivo instrumentation member optical imaging pre-clinical programs research and development research clinical testing research study single photon emission computed tomography

项目摘要

Small Animal Imaging (WUSAIR) Core The Washington University Small Animal Imaging Resource (WUSAIR) is one of the five original Small Animal Imaging Research Program (SAIRP) centers funded in 1999 and was competitively renewed in 2004. WUSAIR provides state-of-the-art facilities and infrastructure for MRI, PET, CT, SPECT and optical imaging of mice, rats and other small laboratory animals. Located in the heart of the Washington University Medical Center, WUSAIR combines instrumental and intellectual capabilities found at few other institutions. WUSAIR serves a broad community of cancer scientists, non-experts in MRI, CT, PET or optical technology, who have a pressing need for quantitative image analysis of small laboratory animal model systems. A particular focus is on mouse and rat models of cancer. WUSAIR also provides research and development at the frontier of imaging technology in an effort to make the most powerful new imaging strategies available to its community of users. WUSAIR imaging modalities are supported by the following operational instrumentation: microPET, microCT, nanoSpect, small animal 4.7 T and 11.74 T MRI, optical absorption, fluorescence, diffuse optical tomography (DOT) and bioluminescence in vivo imaging, and optical microscopy, through both commercial and custom built systems. See resources for a complete listing of instrumentation. The ancillary services and capabilities within WUSAIR include physics and engineering support for the development and design of new hardware and imaging methods; informatics support for local and remote data access, analysis, visualization and archival; new contrast-agent development; biostatistics consultation for experiment planning and data analysis; and animal procedure assistance for surgical procedures, catheter placement and maintenance, and monitoring of physiologic status during imaging experiments. WUSAIR will provide the NTR with comprehensive small-animal imaging resources for development of probes and pre-clinical evaluations and validation of imaging methods. WUSAIR also provides the potential for other members of the NTR-Networks to utilize comprehensive small-animal imaging resources. This will be of particular benefit to institutions lacking in one of the many imaging modalities represented by WUSAIR. Importantly, WUSAIR will help to facilitate new projects quickly and efficiently and thus is compatible with offsite investigators.

小动物成像（WUSAIR）核心