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中文摘要
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描述(由申请人提供):该研究将完成第一个国际纵向双胞胎研究,研究基因和环境对从学前班到幼儿园结束,一年级和二年级(孩子“学习阅读”时)和四年级(孩子“阅读学习”时)的预阅读和早期阅读相关技能的影响。学龄前儿童的注意力、语音意识、快速命名、言语记忆、词汇、语法、形态学和文字知识等方面的数据被用来形成可靠的综合评分和潜在特征,用于并发性和发展性行为遗传分析。在接下来的5年里,我们建议对568对双胞胎完成阅读和相关技能的后续评估,直到二年级结束,并将纵向设计扩展到四年级结束,增加对双胞胎阅读和听力理解的重视,以及他们的印刷品暴露。包括与双胞胎阅读和语言发展相关的环境措施,以帮助确定有助于对共享和非共享环境影响的行为遗传估计的具体因素,并确定阅读和语言发展中潜在的重要基因型环境相关性。科罗拉多研究的双胞胎数据将在适当的时候与澳大利亚和斯堪的纳维亚的平行研究的双胞胎数据进行比较和结合,以更有力地分析个体差异和阅读及相关技能的残疾。先前对年龄较大的儿童和成人进行的双胞胎研究表明,基因对阅读和相关技能的个体差异和群体缺陷都有很强的影响,而环境的影响较弱,但这些影响的发育途径及其对干预的影响尚未得到很好的理解。完成从学龄前到四年级的纵向双胞胎研究将为早期阅读发展关键时期的个体差异和残疾的遗传和环境病因提供重要的新证据。
英文摘要
DESCRIPTION (provided by applicant): The proposed research will complete the first international longitudinal twin study of genetic and environmental influences on pre-reading and early reading-related skills from preschool through the end of kindergarten, 1st, and 2nd grades, when children "learn to read", and at the end of 4th grade, when children "read to learn." Preschool data from measures of attention, phonological awareness, rapid naming, verbal memory, vocabulary, grammar, morphology, and print knowledge are being used to form reliable composite scores and latent traits for concurrent and developmental behavior-genetic analyses. Over the next 5 years, we propose to complete follow-up assessments of reading and related skills for 568 twin pairs through the end of 2nd grade, and extend the longitudinal design to the end of 4th grade with increased emphasis on the twins' reading and listening comprehension, and on their print exposure. Environmental measures related to the twins' reading and language development are included to help identify specific factors that contribute to behavior-genetic estimates of influences from shared and non-shared environment, and to identify potentially important genotype-environment correlations in reading and language development. The twin data from the Colorado study will be compared and combined where appropriate with twin data from parallel studies in Australia and Scandinavia for more powerful analyses of individual differences and disabilities in reading and related skills. Previous twin research with older children and adults has shown strong genetic and weaker environmental influences on both individual differences and group deficits in reading and related skills, but the developmental pathways for these influences and their implications for intervention are not well understood. Completion of the proposed longitudinal twin study from preschool through the 4th grade will provide important new evidence regarding the genetic and environmental etiology of individual differences and disabilities across this critical period of early reading development.
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Differential Diagnosis in Learning Disabilities
  • 批准号:
    8090042
  • 项目类别:
  • 资助金额:
    $107.81万
  • 财政年份:
    2010
  • 负责人:
    RICHARD K OLSON
  • 依托单位:
Differential Diagnosis in Learning Disabilities
  • 批准号:
    7933142
  • 项目类别:
  • 资助金额:
    $23.54万
  • 财政年份:
    2009
  • 负责人:
    RICHARD K OLSON
  • 依托单位:
Longitudinal Twin Study of Early Reading Development (supplement)
  • 批准号:
    7315726
  • 项目类别:
  • 资助金额:
    $19.49万
  • 财政年份:
    2007
  • 负责人:
    RICHARD K OLSON
  • 依托单位:
READING, WRITING AND LANGUAGE PROCESSES
  • 批准号:
    7699792
  • 项目类别:
  • 资助金额:
    $63.45万
  • 财政年份:
    2007
  • 负责人:
    RICHARD K OLSON
  • 依托单位:
海外基金