Continuation of Follow-up of DES-exposed Cohorts

继续对 DES 暴露组进行随访

• 批准号: 7584750
• 金额: $ 26.32万
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-30 至 2010-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7584750
• 关键词: Continuation; Follow; up; DES; exposed

Our overall objectives are to 1) follow-up the second and third generation cohorts at Dartmouth, 2) lead the five-center third generation study, and 3) lead and contribute to manuscript development. Follow-up activities include tracing cohort members, sending questionnaires, conducting telephone interviews, obtaining written consent for medical record access, retrieving medical records, and submitting data to the coordinating center. We will also lead the third generation study. Broadly, this responsibility includes maintaining the third generation cohort registry, overseeing data collection, and documenting operational decisions. We will develop third generation study-related materials, including the study protocol, questionnaire, pathology abstraction forms, and transmittal forms. Incoming data will be entered into electronic files, double-entered, and verified. Questionnaires and non response forms will be reconciled with other data sources, including the cohort registry and the study centers' progress reports. The computerized data will be edited and cleaned, and analyses files will be created and distributed to other centers. We also propose to continue our role in manuscript development. Currently, the Dartmouth study center leads three papers, covering three generations of the cohorts, and additional papers will be undertaken when the follow-up data are mature. We will also continue to contribute to manuscripts initiated at the other study centers.

我们的总体目标是1）随访达特茅斯的第二代和第三代队列，2）领导五中心第三代研究，3）领导和促进手稿开发。随访活动包括追踪队列成员、发送问卷、进行电话访谈、获得病历访问的书面同意、检索病历和向协调中心提交数据。我们还将领导第三代研究。从广义上讲，这一职责包括维护第三代队列登记，监督数据收集和记录操作决策。我们将开发第三代研究相关材料，包括研究方案、问卷、病理学摘要表和传输表。传入数据将输入电子文件，重复输入并验证。问卷和无应答表将与其他数据源进行核对，包括队列登记和研究中心的进展报告。将对计算机化数据进行编辑和清理，并创建分析文件并分发给其他中心。我们还建议继续发挥我们在手稿开发方面的作用。目前，达特茅斯研究中心领导了三篇论文，涵盖了三代人的队列，当后续数据成熟时，将承担更多的论文。我们还将继续为其他研究中心发起的手稿做出贡献。