MRIS

磁共振成像和光谱（MRIS）设施为以下成像提供支持： 细胞、材料、组织、小动物、患者和志愿者。该设施主要服务于UCCRC 研究人员，也包括其他研究领域的研究人员。各种体外和体内 提供的测量包括： (a)基于肿瘤体积的新型治疗效果的临床前和临床评价， 形态学、灌注、毛细血管通透性、来自扩散敏感成像的细胞活力等 测量;（B）组织样本的高分辨率成像;（c）临床前和临床开发 以及测试用于癌症的早期检测和评估的新成像方法，例如新的 动态对比增强MRI（DCEMRI）和光谱/空间成像的方法;（d） 培养中的细胞和组织;以及（e）开发和测试图像引导疗法，包括高 强度聚焦超声该设施拥有经验丰富的工作人员。共同董事，博士。 Greg Karczmar和Brian Roman提供MRI物理和技术，癌症成像， 以及MRI在分子生物学和生理学研究中的应用。临床联合主任， 博士Mitchell是一位经验丰富的放射科医生，具有临床试验专业知识。经验丰富的工作人员包括 临床和临床前成像技术总监，拥有15年以上MRI经验的机构经理 经验丰富，拥有25年经验的高级兽医技术专家，以及一群才华横溢的 技术专家和核磁共振物理学家。合作的跨学科和翻译研究是 重点介绍例如，磁共振成像核心为最近资助的乳腺癌研究提供支持， 导演：Olufunmilayo Olopade博士2007年，该基金的可用资源将为： 戏剧性的升级。林恩号将安装一台最先进的9.4特斯拉小口径扫描仪 S. Florsheim MRIS实验室，该扫描仪将用于临床前研究。这个新 扫描器将显著地增加空间分辨率和/或信噪比，以及距离 可以进行的实验。此外，一种新的1.5特斯拉全身研究扫描仪将 大大提高了临床研究的能力。与此同时，MRIS工作人员将 增加了一名护士协调员和额外的MRI技术人员，以适应 增加研究量。

The Magnetic Resonance Imaging and Spectroscopy (MRIS) Facility provides support for imaging of cells, materials, tissues, small animals, patients, and volunteers. The Facility serves primarily UCCRC investigators, but also investigators in other areas of research. A variety of in vitro and in vivo measurements are offered including: (a) Pre-clinical and clinical evaluation of the effects of novel therapies based on tumor volume, morphology, perfusion, capillary permeability, cell viability from diffusion-sensitive imaging, and other measurements; (b) High resolution imaging of tissue samples; (c) Pre-clinical and clinical development and testing of new imaging methods for early detection and evaluation of cancer, for example novel approaches to Dynamic Contrast Enhanced MRI (DCEMRI) and spectral/spatial imaging; (d) Imaging of cells and tissues in culture; and (e) Development and testing of image-guided therapies including high intensity focused ultrasound. The Facility has an experienced staff. Together the Co-Directors, Drs. Greg Karczmar and Brian Roman provide expertise in MRI physics and technology, cancer imaging, and applications of MRI to study molecular biology and physiology. The Clinical Co-Director, Dr. Mitchell, is an experienced Radiologist with clinical trials expertise. The experienced staff includes Technical Directors for clinical and pre-clinical imaging, a Facility Manager with over 15 years of MRI experience, a Senior Veterinary Technologist with 25 years of experience, and a talented group of technologists and MRI physicists. Collaborative interdisciplinary and translational research is emphasized. For example, the MRIS Core provides support for the recently funded Breast Cancer SPORE, directed by Dr. Olufunmilayo Olopade. In 2007, the resources available to the Facility will be dramatically upgraded. A new state-of-the-art 9.4 Tesla small bore scanner will be installed in the Lynn S. Florsheim MRIS Laboratory, and this scanner will be used for pre-clinical research. This new scanner will significantly increase the spatial resolution and/or signal-to-noise ratio, and also the range of experiments that can be performed. In addition, a new 1.5 Tesla whole body research scanner will dramatically increase the capacity for clinical research. At the same time, the MRIS staff will be increased to include a Nurse Coordinator, and additional MRI technologists, to accommodate the increased volume of research.