PRACTICE-BASED RESEARCH NETWORK

基于实践的研究网络(PBRN)是从事实践工作的临床医生组织 在研究方面。PBRN已成为将研究转化为实践的重要关键 把实践转化为研究。然而，开发和维护以及继续 让忙碌的社区实践参与癌症研究需要专门的专业知识和持续的 支持。因此，PBRN核心设施的任务是： 发展和维持从事癌症研究的以实践为基础的研究网络； ？建议和协助Case综合癌症中心(Case CCC)的研究人员开发 以社区为基础的癌症研究研究，以便在PBRN中实施； ？提供基础设施，支持实施案件CCC调查人员的研究 在PBRN中学习，并支持由网络实践发起的研究。 以实践为基础的研究网络核心设施支持患者、临床医生、 癌症研究中的实践和卫生系统： 1.启动新的PBRN； 2.发展现有PBRN的基础设施； 3.为癌症中心研究人员提供PBRN方法咨询和参与实践； 4.就PBRN研究项目的实施向调查人员提供咨询和协助。 PBRN核心已经启动并维持了8个成功的PBRN，并正在开发5个新的PBRN。这个 已建立的PBRN代表主要的医疗保健系统，并包括联邦合格的家庭医学实践 卫生中心、社区肿瘤学实践、儿科实践和普通牙科实践。 PBRN核心促进了23个资助研究项目的开发和实施 它开发和维持的PBRN。这些项目中有14个由NCI资助，6个 由ACS支持。为这些项目提供的赠款资金总额超过1500万美元。 对PBRN核心服务的需求强劲且不断增长，继续和 扩大该设施的使用范围是非常好的。目前，CCC案的19名成员正在追查15种不同的 调查路线可能导致资助的研究在核心支持的PBRN中实施。

Practice-based research networks (PBRNs) are organizations of clinicians working in practices that engage in research. PBRNs have emerged as a vital lynchpin in efforts to translate research into practice by translating practice into research. However, the development and maintenance and the continued engagement of busy community practices in cancer research requires specialized expertise and ongoing support. Therefore, the mission of the PBRN Core Facility is: ¿ To develop and sustain practice-based research networks that engage in cancer research; ¿ To advise and assist Case Comprehensive Cancer Center (Case CCC) investigators in developing community-based cancer research studies for implementation in PBRNs; ¿ To provide infrastructure that supports the implementation of Case CCC investigators' research studies in PBRNs, and that supports network practice-initiated research. The Practice-Based Research Network Core Facility supports the engagement of patients, clinicians, practices, and health systems in cancer research by: 1. Starting new PBRNs; 2. Developing the infrastructure of existing PBRNs; 3. Providing PBRN methods consultations to Cancer Center investigators and participating practices; 4. Advising and assisting investigators on research project implementation in PBRNs. The PBRN Core has started and sustained 8 successful PBRNs and is developing 5 new PBRNs. The established PBRNs represent major healthcare systems and include family medicine practices, federallyqualified health centers, community oncology practices, pediatrics practices, and general dentistry practices. The PBRN Core has facilitated the development and implementation of 23 funded research projects within the PBRNs that it has developed and sustained. Fourteen of these projects have been funded by NCI, and 6 supported by ACS. Grant funding for these projects totals over $15 million. The demand for the PBRN Core's services is strong and growing, and the potential for continued and expanded use of the facility is excellent. At present, 19 members of the Case CCC are pursuing 15 different lines of inquiry likely to result in funded studies to be implemented in Core-supported PBRNs.