Administration Core

行政核心的作用 行政核心提供行政和智力监督和指导 以及该计划的财务会计。Bette Sheehan女士和Randy Martinson先生提供行政 以及这一核心所需的财务专业知识。 贝特·希恩女士负责监督该项目的社区行政服务。她组织了 由本项目发起和维持的每周学生和博士后研讨会。她负责管理 并促进每个项目完成开展研究所需的不断增加的文档 包括人体安全批准，脊椎动物使用批准，生物安全批准，以及 化学安全审批。她组织项目负责人的会议，将他们的手稿存档，并 监督他们的学生委员会会议。正是这些努力为萨格登博士提供了一种手段 首席调查员，与计划成员进行的最新研究保持同步。他的 与项目负责人举行的每周会议及其合并的每周工作人员会议，这也是组织的 由Sheehan女士提出，为Sugden博士影响该项目的研究提供了第二种手段。希恩女士 还将组织我们的科学顾问委员会成员的访问。我们建议把会员们 单独和有时一起去麦迪逊，以促进我们在癌症研究方面的卓越表现。 兰迪·马丁森先生负责监督该项目拨款的财务会计工作。他提供了 每个项目负责人不断报告他们的预算和支出，并向Sugden博士通报潜在的 在困难发生之前。他在为我们的供货获得最具竞争力的价格方面发挥了重要作用。 使用。例如，他组织了该项目启动与限制性内切酶供应商的合同 这不仅为我们提供了尽可能低的价格，而且还可以立即获得它们，它们是 存储在McArdle中。马丁森先生还指导项目负责人准确预测未来的预算。 在满足联邦和州政府、大学和医疗机构的会计要求方面 管理该方案资金的学校。 智力监督和指导是由这一核心的两个方面提供的。萨格登博士通常会遇到 每周与项目负责人多次讨论科学和人事问题。他是委员会的成员。 广大研究生毕业论文委员会开展本课题的研究工作。 他阅读了许多描述该项目研究初稿的手稿，并建议 在适当情况下进行修订。同样清楚的是，所有的项目负责人都是他们的 因此，萨格登博士已经并将继续为这个项目做出的主要贡献是促进 他们之间的合作。例如，保罗·阿尔奎斯特博士和保罗博士正是通过他的努力 兰伯特和他已经在他们的目标上团结一致，以确定更多可能由 人类肿瘤病毒。 该核心将为其研究提供智力监督和指导的第二个方面 是通过它的科学顾问委员会。4名研究领域与项目领域重叠的专家将前来并 每年都要对该项目的科学进行批判性的审查。迪马约博士是乳头瘤病毒方面的专家，涉猎广泛 对病毒学的总体理解。鲁尼博士是爱泼斯坦-巴尔病毒方面的专家，在 将研究成果发展为治疗EBV相关癌症的有效疗法。他们不是 被要求批评拨款申请，而不是访问和批判性地审查正在进行的研究。这个 项目负责人和主要研究人员将展示他们当前和拟议的研究，供所有人讨论。这个 计划成员希望这些专家同事逐渐了解他们的科学，并帮助他们 合作蓬勃发展。萨格登博士将在每次访问结束时与顾问私下会面，以寻求任何 关于他促进该项目成功的敏感建议。

Role of the Administrative Core The Administrative Core provides both administrative as well as intellectual oversight and guidance and financial accounting for the Program. Ms. Bette Sheehan and Mr. Randy Martinson provide the administrative and financial expertise required for this Core. Ms. Bette Sheehan oversees the communal administrative services for this program. She organizes the weekly student and postdoctoral seminars initiated and maintained by this Program. She administers and facilitates each project's fulfilling the ever-increasing documentation required to carry out our research including human subjects safety approval, vertebrate animal use approval, biological safety approval, and chemical safety approval. She organizes meetings of the project leaders, archiving their manuscripts, and overseeing their students' committee meetings. It is these efforts that provide one means for Dr. Sugden as the principal investigator to stay abreast of the current research carried out by Program members. His weekly meetings with the Project leaders and their combined weekly staff meeting, which is also organized by Ms. Sheehan, provides a second means for Dr. Sugden to affect this Program's research. Ms. Sheehan will also organize the visits of our scientific advisory board members. We propose to bring the members individually and sometimes together to Madison to foster excellence in our cancer research. Mr. Randy Martinson oversees the financial accounting for this Program-Project grant. He provides each project leader ongoing reports of their budgets and expenditures and informs Dr. Sugden of potential difficulties before they occur. He is instrumental in obtaining the most competitive prices for the supplies we use. For example, he organized the Program's initiating a contract with a vendor of restriction endonucleases which provides us not only the lowest possible prices but also immediate access to them, their being stored in McArdle. Mr. Martinson also guides project leaders in their projecting accurately future budgets and in meeting the accounting demands of federal and state governments, the University, and the Medical School through which the Program's funds are administered. Intellectual oversight and guidance is provided by two facets of this core. Dr. Sugden usually meets with project leaders multiple times per week to discuss science and personnel. He is a member on the dissertation committees of the majority of the graduate students carrying out the research of this program. He reads many of the manuscripts describing this program's research in their initial draft form and suggests revisions where appropriate. It is also clear that all of the project leaders are established experts in their fields so that a major contribution Dr. Sugden has and will continue to make to this program is to foster collaboration between them. For example, it is in part through his efforts that Drs. Paul Ahlquist and Paul Lambert and he have united in their goal to identify additional human cancers that may be caused by human tumor viruses. The second facet by which this core will provide intellectual oversight and guidance for its research is through its scientific advisory board. Four experts whose research overlaps project areas shall come and review the program's science critically each year. Dr. DiMaio is an expert in papillomaviruses with a breadth of understanding of virology in general. Dr. Rooney is an expert in Epstein-Barr virus with experience in developing research findings into effective therapies for treating EBV-associated cancers. They are not being asked to critique the grant application but rather to visit and critically review ongoing research. The project leaders and key researchers will present their current and proposed research for all to discuss. The program members want these expert colleagues to grow to know their science and .to help their collaborations flourish. Dr. Sugden will meet privately with the advisors at the end of each visit to seek any sensitive suggestions about his fostering the success of the program.