Administration Core

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Role of the Administrative Core The Administrative Core provides both administrative as well as intellectual oversight and guidance and financial accounting for the Program. Ms. Bette Sheehan and Mr. Randy Martinson provide the administrative and financial expertise required for this Core. Ms. Bette Sheehan oversees the communal administrative services for this program. She organizes the weekly student and postdoctoral seminars initiated and maintained by this Program. She administers and facilitates each project's fulfilling the ever-increasing documentation required to carry out our research including human subjects safety approval, vertebrate animal use approval, biological safety approval, and chemical safety approval. She organizes meetings of the project leaders, archiving their manuscripts, and overseeing their students' committee meetings. It is these efforts that provide one means for Dr. Sugden as the principal investigator to stay abreast of the current research carried out by Program members. His weekly meetings with the Project leaders and their combined weekly staff meeting, which is also organized by Ms. Sheehan, provides a second means for Dr. Sugden to affect this Program's research. Ms. Sheehan will also organize the visits of our scientific advisory board members. We propose to bring the members individually and sometimes together to Madison to foster excellence in our cancer research. Mr. Randy Martinson oversees the financial accounting for this Program-Project grant. He provides each project leader ongoing reports of their budgets and expenditures and informs Dr. Sugden of potential difficulties before they occur. He is instrumental in obtaining the most competitive prices for the supplies we use. For example, he organized the Program's initiating a contract with a vendor of restriction endonucleases which provides us not only the lowest possible prices but also immediate access to them, their being stored in McArdle. Mr. Martinson also guides project leaders in their projecting accurately future budgets and in meeting the accounting demands of federal and state governments, the University, and the Medical School through which the Program's funds are administered. Intellectual oversight and guidance is provided by two facets of this core. Dr. Sugden usually meets with project leaders multiple times per week to discuss science and personnel. He is a member on the dissertation committees of the majority of the graduate students carrying out the research of this program. He reads many of the manuscripts describing this program's research in their initial draft form and suggests revisions where appropriate. It is also clear that all of the project leaders are established experts in their fields so that a major contribution Dr. Sugden has and will continue to make to this program is to foster collaboration between them. For example, it is in part through his efforts that Drs. Paul Ahlquist and Paul Lambert and he have united in their goal to identify additional human cancers that may be caused by human tumor viruses. The second facet by which this core will provide intellectual oversight and guidance for its research is through its scientific advisory board. Four experts whose research overlaps project areas shall come and review the program's science critically each year. Dr. DiMaio is an expert in papillomaviruses with a breadth of understanding of virology in general. Dr. Rooney is an expert in Epstein-Barr virus with experience in developing research findings into effective therapies for treating EBV-associated cancers. They are not being asked to critique the grant application but rather to visit and critically review ongoing research. The project leaders and key researchers will present their current and proposed research for all to discuss. The program members want these expert colleagues to grow to know their science and .to help their collaborations flourish. Dr. Sugden will meet privately with the advisors at the end of each visit to seek any sensitive suggestions about his fostering the success of the program.