Safe Use of Medications in Primary Care Practices

医疗差错是一种常见的医疗差错，具有巨大的社会负担。据估计 每年有77万美国人经历导致伤害或死亡的药物不良事件，总成本为 20亿美元。这些统计数据使减少用药差错成为国家优先事项。因为 门诊环境中开出的药物数量，以及因为大多数用药差错数据 来自住院环境，医学研究所呼吁对用药差错进行更多研究 在门诊环境中。这份K08申请概述了一个五年计划，以支持一位已经 致力于门诊用药安全性的临床研究。候选人是一名临床药剂师， 在初级保健方面有10年的工作经验和专业培训，并得到学术上的大力支持 部门。此外，她在教授药物治疗和指导实践方面拥有丰富的经验- 基于对用药安全性的研究。职业发展计划提供了一系列仔细的 选定的培训和指导经验，包括博士级别的卫生服务研究课程， 指导研究导致合作研究和出版物，以及专业网络，这将 使她的研究成果更上一层楼。她提出的研究计划，安全使用 初级保健实践中的用药有三个具体目标：1)确定示范方法和 用于药物调节的样本(即，捕获和解决药物中的差异 实际服用和记录在患者病历中的)；2)评估 初级保健患者服用多种药物的用药协调的示范方法；以及3) 传播研究结果，并在开展结果试验的提案中扩大这项工作的范围。

Medication error, a common type of medical error, carries a tremendous social burden. An estimated 770,000 Americans each year experience adverse drug events that result in injury or death at a total cost of $2 billion. These statistics have made the reduction of medication errors a national priority. Because of the number of medications prescribed in the outpatient setting and because most data on medication errors come from the inpatient setting, the Institute of Medicine has called for more research on medication errors in the outpatient setting. This K08 application outlines a five-year plan to support a candidate who is already contributing to clinical research on outpatient medication safety. The candidate is a clinical pharmacist with 10 years of working experience and specialty training in primary care and strong support from her academic department. In addition, she has substantial experience teaching pharmacotherapy and conducting practice- based research on medication safety. The career development plan provides a sequence of carefully selected training and mentoring experiences, including doctoral-level health services researchcoursework, mentored research leading to collaborative studies and publications, and professional networking, that will catapult her to the next level of research achievement. Her proposed research program, Safe Use of Medications in Primary Care Practices, has three specific aims: 1) to identify exemplary methods and exemplars for medication reconciliation (i.e., capturing and resolving discrepancies in the medications actually being taken and those recorded in patients' medical records); 2) to evaluate the feasibility of exemplary methods for medication reconciliation on primary care patients taking multiple medications; and 3) to disseminate study results and to extend the scope of this work in proposals to conduct outcomes trials.