Safe Use of Medications in Primary Care Practices

用药错误是一种常见的医疗错误，带来了巨大的社会负担。估计 每年有 770,000 名美国人经历药物不良事件，导致受伤或死亡，总成本为 20亿美元。这些统计数据使减少用药错误成为国家优先事项。因为 门诊开出的药物数量以及大多数有关用药错误的数据 来自住院患者的情况，医学研究所呼吁对用药错误进行更多研究 在门诊环境中。这份 K08 申请概述了一个五年计划，以支持已经成为候选人的候选人 为门诊用药安全的临床研究做出贡献。候选人是一名临床药剂师 10年初级保健工作经验和专业培训以及学术的大力支持 部门。此外，她在药物治疗教学和实践方面拥有丰富的经验- 基于用药安全性的研究。职业发展计划提供了一系列仔细的 精选的培训和指导经验，包括博士级卫生服务研究课程， 指导研究导致合作研究和出版物以及专业网络，这将 将她的研究成就提升到一个新的水平。她提出的研究计划“安全使用” 初级保健实践中的药物具有三个具体目标：1）确定示范方法和 药物协调的范例（即捕获并解决药物中的差异 实际采集的数据以及记录在患者病历中的数据）； 2）评估可行性 对服用多种药物的初级保健患者进行药物协调的示范方法；和 3) 传播研究结果并在开展结果试验的提案中扩大这项工作的范围。

Medication error, a common type of medical error, carries a tremendous social burden. An estimated 770,000 Americans each year experience adverse drug events that result in injury or death at a total cost of $2 billion. These statistics have made the reduction of medication errors a national priority. Because of the number of medications prescribed in the outpatient setting and because most data on medication errors come from the inpatient setting, the Institute of Medicine has called for more research on medication errors in the outpatient setting. This K08 application outlines a five-year plan to support a candidate who is already contributing to clinical research on outpatient medication safety. The candidate is a clinical pharmacist with 10 years of working experience and specialty training in primary care and strong support from her academic department. In addition, she has substantial experience teaching pharmacotherapy and conducting practice- based research on medication safety. The career development plan provides a sequence of carefully selected training and mentoring experiences, including doctoral-level health services researchcoursework, mentored research leading to collaborative studies and publications, and professional networking, that will catapult her to the next level of research achievement. Her proposed research program, Safe Use of Medications in Primary Care Practices, has three specific aims: 1) to identify exemplary methods and exemplars for medication reconciliation (i.e., capturing and resolving discrepancies in the medications actually being taken and those recorded in patients' medical records); 2) to evaluate the feasibility of exemplary methods for medication reconciliation on primary care patients taking multiple medications; and 3) to disseminate study results and to extend the scope of this work in proposals to conduct outcomes trials.