Effects of Literacy on Medication Safety In the Elderly

识字率对老年人用药安全的影响

• 批准号: 6960084
• 负责人: GRACE M. KUO
• 金额: $ 6.15万
• 依托单位: BAYLOR COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-08-01 至 2007-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6960084
• 关键词: African American; Hispanic Americans; behavioral /social science research tag; caucasian American; clinical research; data collection methodology /evaluation; disease /disorder prevention /control; drug adverse effect; functional ability; health care quality; health education; health services research tag; human old age (65+); human population study; human subject; interview; managed care; outcomes research; outpatient care; patient care management; patient safety /medical error; racial /ethnic difference; self care; socioeconomics

DESCRIPTION (provided by applicant): The elderly account for 1/3rd of prescription drug consumption in the United States and are at greater risk for medication errors (MEs) and adverse drug events (ADEs). They are also more likely to have low health literacy that increases the possibility of medication-related problems. Data on MEs and ADEs are collected predominantly in hospitals where it is easier to monitor such errors and to identify patients experiencing medication-related problems. This approach is not optimal in the United States, because here most medications are prescribed in the outpatient setting by primary care physicians. The proposed study will describe the spectrum of MEs and ADEs in the elderly and how health literacy affects medication safety. The aim of this application is to determine the frequency, type, severity, and preventability of MEs among elderly primary care patients who have low (inadequate and marginal) functional health literacy (FHL) vs. elderly primary care patients who have adequate FHL. Furthermore, we will conduct cognitive interviews to understand why MEs may have occurred. The study will be conducted in a primary care research network, the Southern Primary care Urban Research Network (SPUR-NetSM), which is located in Houston, Texas. In this application, we propose to evaluate medications used by 300 elderly patients from diverse ethnic and socioeconomic backgrounds who are seen by primary care providers in outpatient clinics. This is a unique study, because our main outcome measure is ME as it occurs in primary care clinics;. Moreover, we will generate findings and compare types and rates of MEs and ADEs among elderly patients who have different ethnicity, socioeconomic status, and literacy. Findings from this study will be used to design interventions for medication-safety-promotion education programs to be implemented and evaluated within primary care clinics. The proposed research is innovative, because it will provide an understanding of MEs and ADEs in a diverse primary care population and the association of health literacy with such errors. The outcomes of the proposed research will be significant, because millions of the American elderly will receive improved quality of care.

描述（由申请人提供）：老年人占美国处方药消费量的 1/3，并且出现用药错误 (ME) 和药物不良事件 (ADE) 的风险更大。他们的健康素养也可能较低，这增加了出现药物相关问题的可能性。 ME 和 ADE 的数据主要在医院收集，在那里更容易监控此类错误并识别遇到药物相关问题的患者。这种方法在美国并不是最佳选择，因为在这里大多数药物都是由初级保健医生在门诊开出的。拟议的研究将描述老年人的 ME 和 ADE 范围以及健康素养如何影响用药安全。本应用的目的是确定功能健康素养 (FHL) 较低（不足和边缘）的老年初级保健患者与具有足够 FHL 的老年初级保健患者之间 ME 的频率、类型、严重程度和可预防性。此外，我们将进行认知访谈，以了解 ME 发生的原因。该研究将在初级保健研究网络——南部初级保健城市研究网络（SPUR-NetSM）中进行，该网络位于德克萨斯州休斯顿。在此应用中，我们建议评估 300 名来自不同种族和社会经济背景的老年患者使用的药物，这些患者由初级保健提供者在门诊诊所就诊。这是一项独特的研究，因为我们的主要结果指标是初级保健诊所中发生的 ME；。此外，我们将得出研究结果并比较不同种族、社会经济地位和识字率的老年患者的 ME 和 ADE 的类型和发生率。这项研究的结果将用于设计药物安全促进教育计划的干预措施，并在初级保健诊所内实施和评估。拟议的研究具有创新性，因为它将提供对不同初级保健人群中 ME 和 ADE 的理解以及健康素养与此类错误之间的关联。拟议研究的结果将是重大的，因为数百万美国老年人将获得更好的护理质量。