Southeast Cancer Control Consortium, Inc

描述(由申请人提供)： 东南癌症控制联盟(SCCC)是一个由美国国家癌症研究所(NCI)资助了17年的社区临床肿瘤学项目(CCOP)。SCCC是由18个组成部分/社区和22个机构组成的联盟，位于美国东南部的五个州地区。SCCC的长期目标是将最先进的癌症临床试验和预防计划带到小型社区机构的竞技场，以增加获得NCI批准的癌症计划的机会。转介社区的人口估计为970万人，人口结构反映出人口密度低，社会经济和教育发展有限，女性比例超过50%，非裔美国人到白人人口大约是全国平均水平的两倍。这为增加少数群体参与研究和保持妇女参与研究提供了机会。有121名内科医生(内科肿瘤学家、外科医生、放射肿瘤学家和泌尿科医生)参加了SCCC。每个机构都有一名医生被指定为“社区领袖”，负责在当地协调参与SCCC计划。每个社区领导人都有一个由人员组成的支持团队(肿瘤学护士和临床研究助理/CRA)，他们接受了SCCC运营办公室工作人员的培训，了解遵守联邦和研究基地法规的适当程序。社区支持小组的工作由社区领导人的对应人员协调和监督，他们是当地的“研究协调员”，即肿瘤科护士或CRA。SCCC运营办公室通过以下方式协调联合体的活动：为成员问题提供电话和电子邮件信息服务、传真通信、监测机构审查委员会(IRB)的批准、通过每周邮件和每月协议邮件促进协议参与、进行现场访问、提供数据管理培训和继续教育计划、准备拨款申请和报告，以及协调研究基地审计。SCCC运营办公室从NCI批准的八个CCOP研究基地为社区提供癌症治疗和预防的研究基础研究。每个社区都有由当地IRB审查的这些研究，所有这些研究都得到了人类研究保护办公室(OHRP)的批准。社区领导人和研究协调员对当地成员进行教育，并促进这些研究在社区内的实施。通过庞大的联盟网络，有信心SCCC计划将显著提高NCI批准的社区环境中最先进的癌症护理和预防研究的质量和获得机会。其目标是能够通过克服种族、少数民族、性别和社会经济障碍来降低癌症的发病率和死亡率。

DESCRIPTION (provided by applicant): The Southeast Cancer Control Consortium, Inc. (SCCC) is a Community Clinical Oncology Program (CCOP) funded for the past 17 years by the National Cancer Institute (NCI). The SCCC is a consortium of 18 components/communities and 22 institutions in a five-state area of the southeast United States. The SCCC's long-term objective is to bring state-of-the-art clinical trails and prevention programs for cancer to an arena of small community institutions to increase access to NCI approved cancer programs. The catchment of the referral communities is estimated at 9.7 million, with demographics reflecting a low population density, limited socioeconomic and educational development, female percentage greater than 50 percent, and an African American to white population approximately twice the national average. This provides an opportunity to increase minority access and maintain inclusion of women to research studies. There are 121 physicians (medical oncologists, surgeons, radiation oncologists, and urologists) participating in the SCCC. Each institution has a physician designated as the "Community Leader", responsible for locally coordinating participation in the SCCC program. Each Community Leader has a support team of personnel {oncology nurses and clinical research associates/CRAs) who are trained by the SCCC Operations Office staff, in proper procedures for compliance to federal and research base regulations. The community support teams' efforts are coordinated and monitored by the Community Leaders' counterpart, an oncology nurse or CRA, who is the local "Study Coordinator." The SCCC Operations Office coordinates the consortium's activities by providing a telephone and email information service line for members' questions, fax machine communication, monitoring Institutional Review Board (IRB) approvals, facilitating protocol participation via weekly mailings and monthly protocol mailings, conducting on-site visits, providing data management training and continuing education programs, preparing grant applications and reports, and coordinating research base audits. The SCCC Operations Office provides the communities with research base studies, for both cancer treatment and prevention, from the eight CCOP research bases approved by NCI. Each community has these studies reviewed by their local IRB, all of which are approved by the Office for Human Research Protections (OHRP). The Community Leaders and Study Coordinators educate local members and facilitate implementation of these studies within the communities. Through the expansive consortium network, there is confidence that the SCCC program will significantly improve the quality of and access to NCI-approved state-of-the-art cancer care and prevention studies in the community setting. The goal is to be able to reduce the morbidity and mortality of cancer by overcoming ethnic, minority, gender, and socioeconomic barriers.