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PHI-56: NCI #6813: A PHASE I PHARMACOKINETIC AND PHARMACODYNAMIC STUDY OF TEMS

PHI-56: NCI #6813: A PHASE I PHARMACOKINETIC AND PHARMACODYNAMIC STUDY OF TEMS
PHI-56：国家癌症研究所
批准号：
7982074
负责人：
Stephen I Shibata
金额：
$10.78万
依托单位：
UNIVERSITY OF SOUTHERN CALIFORNIA
依托单位国家：
美国
项目类别：
财政年份：
2008
资助国家：
美国
项目状态：
已结题
起止时间：
2008-12-01 至 2009-11-30
来源：
https://reporter.nih.gov/project-details/7982074
关键词：
CCI-779Clinical ResearchComputer Retrieval of Information on Scientific Projects DatabaseDoseDrug KineticsFunctional disorderFundingGrantHepaticInstitutionPatientsPharmacodynamicsPhasePopulationRecommendationResearchResearch PersonnelResourcesSafetySourceUnited States National Institutes of Healthcohort

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中文摘要
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英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The primary objective of this study is to evaluate the safety, tolerability and to establish the maximum tolerated recommended dose (RD) of CCI-779 (temsirolimus) in cohorts of patients with varying degrees of hepatic dysfunction (mild, moderate and severe) in order to provide appropriate dosing recommendations for CCI-779 in this population.
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A PHASE I PHARMACOKINETIC STUDY OF PS-341 IN PATIENTS WITH ADVANCED
  • 批准号：
    7716658
  • 项目类别：
  • 资助金额：
    $4.45万
  • 财政年份：
    2008
  • 负责人：
    Stephen I Shibata
  • 依托单位：
    UNIVERSITY OF SOUTHERN CALIFORNIA
CLINICAL TRIAL: NCI #5874, PHI-43: "A PHASE I PHARMACOKINETIC STUDY OF PS341 IN
  • 批准号：
    7716646
  • 项目类别：
  • 资助金额：
    $1.68万
  • 财政年份：
    2008
  • 负责人：
    Stephen I Shibata
  • 依托单位：
    UNIVERSITY OF SOUTHERN CALIFORNIA
CLINICAL TRIAL: PILOT PHARMACOKINETIC STUDY OF DOSE ADJUSTMENT OF VINORELBINE IN
  • 批准号：
    7982057
  • 项目类别：
  • 资助金额：
    $0.23万
  • 财政年份：
    2008
  • 负责人：
    Stephen I Shibata
  • 依托单位：
    UNIVERSITY OF SOUTHERN CALIFORNIA
CLINICAL TRIAL: NCI #5874, PHI-43: "A PHASE I PHARMACOKINETIC STUDY OF PS341 IN
  • 批准号：
    7982061
  • 项目类别：
  • 资助金额：
    $1.62万
  • 财政年份：
    2008
  • 负责人：
    Stephen I Shibata
  • 依托单位：
    UNIVERSITY OF SOUTHERN CALIFORNIA
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