NATIONAL DRUG ABUSE TREATMENT CLINICAL TRIALS NETWORK

总体目标是通过继续开展工作来补充NIDA临床试验网络（CTN）的目标 北卡罗来纳州节点的一部分，并将其扩展到农村南部节点。区域研究与培训 中心将设在杜克。合作伙伴将包括社区治疗计划（CTPs）， 在南方9个州的农村和小城市地区向各种服务不足的人口提供服务 （亚拉巴马、阿肯色州、格鲁吉亚、路易斯安那、密西西比、北卡罗来纳州、南卡罗来纳州、田纳西州和 弗吉尼亚州）拥有美国25%的农村人口和45%的非裔美国人。具体 目标是： 1.确定和推荐基于研究和实践的方案（特别是在以下领域） 甲基苯丙胺的使用，艾滋病毒/艾滋病，远程医疗，共同发生的疾病，和处方阿片类药物）的试验， CTN，并支持相关的平台研究。 2：支持和发展至少2名门诊病人、1名住院病人和1名阿片类药物的能力 每个州的替换程序参与基于CTN的协议。重点将是高效审判 从多元化的学科人才库中招募人才，并提供高质量的数据。 3：探讨可提高临床试验效率、忠实性和完整性的方法学问题， 农村这方面的例子包括便利获得服务不足的少数群体人口 4：与各种组织合作，促进采用循证实践， 特别是那些在CTN内研究的，在这些服务不足的地区。这将包括继续和 扩大现有的传播工作。 5：增加参与药物滥用临床和服务研究的年轻调查人员的人数。 在这方面，NC节点通过少数民族补助金和K奖指导年轻调查员。 农村南部节点将扩大CTN的包容性和普遍性。的发展 这项事业将贡献大量的知识，并有助于填补长期被忽视的真空， 传统上被忽视的人群，在研究和循证治疗范围内， 滥用药物

The overall goal is to complement the aims of the NIDA Clinical Trial Network (CTN) by continuing the work of the North Carolina Node and expanding it into a Rural South Node. The Regional Research and Training Center will be based at Duke. Partners will include community treatment Programs (CTPs) that will provide access to diverse underserved populations in rural and small urban areas in the 9 Southern States (Alabama, Arkansas, Georgia, Louisiana, Mississippi, North Carolina, South Carolina, Tennessee and Virginia) that have 25% of the rural and 45% of the rural African American population in the US. The specific aims are: 1. To identify and recommend research and practice-based protocols (particularly in the areas of methamphetamine use, HIV/AIDS, telemedicine, co-occurring disorders, and prescription opioids) for trials in the CTN, and support related platform studies. 2: To support and develop the capabilities of at least 2 outpatient, 1 residential/inpatient and 1 opioid replacement program in each state to participate in CTN-based protocols. The focus will be efficient trial performance to meet the target recruitment from a diverse subject pool and delivery of quality data. 3: To explore the methodological issues that can improve the efficiency, fidelity and integrity of trials in the rural areas. Examples include facilitating access to underserved minority populations 4: To collaborate with a variety of organizations to facilitate the adoption of evidence based practices, especially those studied within the CTN, in these underserved areas. This will include continuing and expanding the existing dissemination efforts. 5: To expand the number of young investigators involved in substance abuse clinical and services research. In this context, the NC node has mentored young investigators through minority supplements.and K awards. The Rural South Node will broaden the inclusiveness and generalizability of the CTN. The development of this undertaking will contribute substantial knowledge and help fill a long neglected vacuum of bringing traditionally neglected populations within the reach of research and evidence-based treatments for substance abuse.