Molecular Genetics of Human Sexual Differentiation

人类性别分化的分子遗传学

• 批准号: nhmrc : GNT1154870
• 负责人: Prof Vincent Harley
• 金额: $ 79.23万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Research Fellowships
• 财政年份: 2019
• 资助国家: 澳大利亚
• 起止时间: 2019-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/molecular-genetics-human-sexual-differentiation/1349163
• 关键词: Molecular; Genetics; Human; Sexual; Differentiation

Whether we are born male or female affects our sense of social place, behaviour, gender identity, reproductive options, and disease susceptibility. I am a molecular geneticist investigating the biology of gender. I identify the genetic causes of ‘intersex’ and transsex conditions and the mechanisms underpinning sexual development, towards improved clinical management. I study how the levels of male genes contribute to male bias in Parkinson’s disease and towards developing a gene therapy.

生为男性还是女性会影响我们的社会地位、行为、性别认同、生殖选择和疾病易感性。我是研究性别生物学的分子遗传学家。我确定了“双性人”和变性条件的遗传原因和性发展的基础机制，以改善临床管理。我研究男性基因水平如何导致帕金森病中的男性偏见，并朝着开发基因治疗的方向发展。