Molecular Genetics of Human Sexual Differentiation

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Whether we are born male or female affects our sense of social place, behaviour, gender identity, reproductive options, and disease susceptibility. I am a molecular geneticist investigating the biology of gender. I identify the genetic causes of ‘intersex’ and transsex conditions and the mechanisms underpinning sexual development, towards improved clinical management. I study how the levels of male genes contribute to male bias in Parkinson’s disease and towards developing a gene therapy.