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Pilot Project Component

Pilot Project Component
试点项目组成部分
批准号:
7499415
负责人:
DAVID W CRABB
金额:
$8.66万
依托单位国家:
美国
项目类别:
财政年份:
2007
资助国家:
美国
项目状态:
已结题
起止时间:
2007-12-01 至 2012-11-30
关键词:
3-DimensionalAcuteAdultAdvisory CommitteesAffectAgeAgonistAlcohol consumptionAlcohol dependenceAlcoholismAlcoholsAlgorithmsAllelesAnatomyAnimal ModelAnimalsAreaArtificial IntelligenceBehavioralBenzodiazepine ReceptorBiological Neural NetworksBloodBrainBrain InjuriesBudgetsCartilageCharacteristicsChildChronicClinicalComplementComputer softwareComputer-Assisted Image AnalysisConditionConsumptionCorpus striatum structureCountryCuesDataData AnalysesDefectDeformityDevelopmentDevelopmental ProcessDiagnosisDiazepamDimensionsDopamineDoseDysmorphologyE-CadherinE-Cadherin Staining MethodEarEmbryoEmbryonic DevelopmentEndocytosisEthanolExperimental Animal ModelExtramural ActivitiesEyeFaceFamily history ofFetal Alcohol ExposureFetal Alcohol Spectrum DisorderFetal Alcohol SyndromeFishesFlumazenilFundingFunding MechanismsGABA AntagonistsGABA ReceptorGene ExpressionGenesGeneticGenetic DeterminismGenetic PolymorphismGenotypeGoalsGrowthHematopoieticHemoglobinHemoglobin concentration resultHeterogeneityHourHumanHuman GeneticsImageImaging TechniquesImaging technologyIn VitroIndianaIndividualLaboratoriesLabyrinthLimb BudLimb structureMaintenanceMeasurementMeasuresMedical ImagingMental RetardationMethodologyMethodsMicroscopyMissionModelingMoodsMotivationMusNaltrexoneNervous System TraumaNeuraxisNoseNumbersOpioid ReceptorOrganOutcomePathway interactionsPatient Self-ReportPatientsPatternPattern Recognition SystemsPectoralPerceptionPerformancePharmaceutical PreparationsPhenotypePilot ProjectsPliabilityPopulationPrincipal InvestigatorProceduresProtocols documentationRaceRangeRateReceptor GeneRecruitment ActivityReproducibilityResearchResearch PersonnelResearch Project GrantsResolutionRetinaldehydeRiskRisk FactorsSample SizeSamplingSelf AdministrationSelf-AdministeredSenior ScientistSignal TransductionSkeletonStagingStructureSupport of ResearchSurfaceSystemTechnologyTestingThinkingTimeTrainingTransgenic OrganismsTreatment outcomeTretinoinUnited States National Institutes of HealthVentral StriatumVomer bone structureX-Ray Computed TomographyXenopusZebrafishalcohol abuse therapyalcohol effectalcohol exposurealcohol researchalcohol responsebasebiobehaviorcell motilitycraniofacialcravingdaydesigndrinkingdrinking behaviorgenome sequencinghuman studyhuman subjectimprovedin uteroin vivoinnovationinterestknockout genemalformationmutantnegative moodneurobehavioralneurochemistrynew technologynovelnovel strategiesproblem drinkerprogramsreceptor functionrelating to nervous systemresearch studyresponsesizesomitogenesissuccesstomographytwo-dimensionalvapor

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英文摘要
The Pilot Project Component will continue through years 21-25 (2007-2012) of the Indiana Alcohol Research Center (IARC). This Component is a mechanism for funding promising, innovative research projects, for attracting new investigators to the alcohol research field, for developing methodologies that can be used by investigators in the IARC as well as investigators all over the country, and for exploring areas of long-range relevance to the overall aims of the IARC. The flexibility inherent in the Pilot Project mechanism has allowed the IARC to respond rapidly to unique scientific opportunities as they have arisen and to support research projects with good potential for evolving into extramurally funded research programs. The IARC Pilot Project Component has had a demonstrably strong stimulatory effect on the growth of alcohol research on the ID campus over the past 19 years. There has been a remarkable rate of success in obtaining independent extramural funding, subsequent to the receipt of IARC pilot funding, for both new investigators as well as for more senior scientists who have entered new alcohol-related research arenas. Based on past performance, we anticipate that this component will result in continued growth of the IARC research program in important new directions. The Administrative Core is responsible for managing the pilot projects which are under the direction of Jan Froehlich with input from David Crabb, Sean O'Connor, Larry Lumeng, and when needed, the Advisory Committee.
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