CLINICAL TRIAL: METABOLIC EFFECTS OF SHORT-TERM WALNUT CONSUMPTION IN METABOLIC
CLINICAL TRIAL: METABOLIC EFFECTS OF SHORT-TERM WALNUT CONSUMPTION IN METABOLIC
批准号:
7718926
负责人:
CHRISTOS S MANTZOROS
金额:
$2.02万
依托单位国家:
美国
项目类别:
财政年份:
2008
资助国家:
美国
项目状态:
已结题
起止时间:
2008-04-01 至 2008-05-31
关键词:
ArginineBiological MarkersBlood VesselsBody WeightClinical TrialsComputer Retrieval of Information on Scientific Projects DatabaseConsumptionCross-Over StudiesDepthFatty acid glycerol estersFundingGrantHealthInflammatoryInstitutionJuglansLipidsMacronutrients NutritionMagnesiumMetabolicMetabolic syndromeMicronutrientsNutrientNutsObservational StudyOutcomePhytochemicalPlacebo ControlResearchResearch PersonnelResourcesSourceTreesUnited States National Institutes of HealthWomancardiovascular disorder riskinsulin sensitivitymen
中文摘要
这个子项目是众多研究子项目之一
英文摘要
This subproject is one of many research subprojects utilizing the
resources provided by a Center grant funded by NIH/NCRR. The subproject and
investigator (PI) may have received primary funding from another NIH source,
and thus could be represented in other CRISP entries. The institution listed is
for the Center, which is not necessarily the institution for the investigator.
Extensive epidemiologic evidence suggests that nut consumption decreases cardiovascular disease risk (CVD) and CVD outcomes. Tree nuts have some similar attributes, but differ in their magnesium, L-arginine, omega-three and other fat fractions. Walnuts have an optimal nutrient content to exert positive health effects. Walnuts have been shown to have a favorable effect on lipid profile and vascular reactivity but these effects alone do not explain the positive health effects observed in observational studies. In addition, the effect of walnuts on the metabolic syndrome as a whole has never been studied. To date the mechanisms of the effects of walnuts on inflammatory biomarkers, body weight and insulin sensitivity remain unknown. Walnuts include many potentially beneficial micronutrients and phytochemicals and in this study we propose to examine the effects of walnuts independent of macronutrient content. We plan to perform a placebo controlled cross-over study to examine in depth the short-term effects of walnut consumption in men and women with the metabolic syndrome.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Leptin Signaling in Humans
-
批准号:8244948
-
项目类别:
-
资助金额:$0.0万
-
财政年份:2011
-
负责人:CHRISTOS S MANTZOROS
-
依托单位:
Leptin Signaling in Humans
-
批准号:8698369
-
项目类别:
-
资助金额:$0.0万
-
财政年份:2011
-
负责人:CHRISTOS S MANTZOROS
-
依托单位:
Leptin Signaling in Humans
-
批准号:8138206
-
项目类别:
-
资助金额:$0.0万
-
财政年份:2011
-
负责人:CHRISTOS S MANTZOROS
-
依托单位:
Leptin Signaling in Humans
-
批准号:8392976
-
项目类别:
-
资助金额:$0.0万
-
财政年份:2011
-
负责人:CHRISTOS S MANTZOROS
-
依托单位:
Role of leptin in the neuroendocrine response to fasting
-
批准号:8037912
-
项目类别:
-
资助金额:$10.21万
-
财政年份:2010
-
负责人:CHRISTOS S MANTZOROS
-
依托单位:
Role of leptin in the neuroendocrine response to fasting
-
批准号:7991587
-
项目类别:
-
资助金额:$10.0万
-
财政年份:2009
-
负责人:CHRISTOS S MANTZOROS
-
依托单位:
The Role of Leptin in the Maintenance of a Reduced Body Weight
-
批准号:8286384
-
项目类别:
-
资助金额:$35.41万
-
财政年份:2008
-
负责人:CHRISTOS S MANTZOROS
-
依托单位:
CLINICAL TRIAL: LEPTIN (R-METHULEPTIN) FOR THE TREATMENT OF HYPOTHALAMIC AMENHOR
-
批准号:7718894
-
项目类别:
-
资助金额:$1.15万
-
财政年份:2008
-
负责人:CHRISTOS S MANTZOROS
-
依托单位:
Adipokine physiology
-
批准号:9177787
-
项目类别:
-
资助金额:$18.11万
-
财政年份:2008
-
负责人:CHRISTOS S MANTZOROS
-
依托单位:
Adipokine physiology
-
批准号:9294048
-
项目类别:
-
资助金额:$18.08万
-
财政年份:2008
-
负责人:CHRISTOS S MANTZOROS
-
依托单位:
The Role of Leptin in the Maintenance of a Reduced Body Weight
-
批准号:7653727
-
项目类别:
-
资助金额:$36.13万
-
财政年份:2008
-
负责人:CHRISTOS S MANTZOROS
-
依托单位:
The Role of Leptin in the Maintenance of a Reduced Body Weight
-
批准号:7858113
-
项目类别:
-
资助金额:$35.76万
-
财政年份:2008
-
负责人:CHRISTOS S MANTZOROS
-
依托单位:
Adipokine physiology
-
批准号:9511793
-
项目类别:
-
资助金额:$18.05万
-
财政年份:2008
-
负责人:CHRISTOS S MANTZOROS
-
依托单位:
Leptin and Adipokine Physiology
-
批准号:7686914
-
项目类别:
-
资助金额:$13.01万
-
财政年份:2008
-
负责人:CHRISTOS S MANTZOROS
-
依托单位:
IN VIVO LEPTIN SIGNALING IN HUMANS AFTER ACUTE LEPTIN ADMINISTRATION
-
批准号:7718888
-
项目类别:
-
资助金额:$0.23万
-
财政年份:2008
-
负责人:CHRISTOS S MANTZOROS
-
依托单位:
Leptin and Adipokine Physiology
-
批准号:8138345
-
项目类别:
-
资助金额:$13.01万
-
财政年份:2008
-
负责人:CHRISTOS S MANTZOROS
-
依托单位:
Leptin and Adipokine Physiology
-
批准号:7510658
-
项目类别:
-
资助金额:$13.01万
-
财政年份:2008
-
负责人:CHRISTOS S MANTZOROS
-
依托单位:
CLINICAL TRIAL: INSULIN SENSITIZERS AND LEPTIN IN HAART-INDUCED LIPATROPHY
-
批准号:7718908
-
项目类别:
-
资助金额:$0.94万
-
财政年份:2008
-
负责人:CHRISTOS S MANTZOROS
-
依托单位:
CLINICAL TRIAL: COFFEE AND GLUCOSE TOLERANCE
-
批准号:7718920
-
项目类别:
-
资助金额:$0.53万
-
财政年份:2008
-
负责人:CHRISTOS S MANTZOROS
-
依托单位:
The Role of Leptin in the Maintenance of a Reduced Body Weight
-
批准号:8110668
-
项目类别:
-
资助金额:$35.41万
-
财政年份:2008
-
负责人:CHRISTOS S MANTZOROS
-
依托单位:
海外基金