FOCAL DYSTONIA: GENOTYPE-PHENOTYPE CORRELATION
FOCAL DYSTONIA: GENOTYPE-PHENOTYPE CORRELATION
批准号:
7731292
负责人:
NUTAN SHARMA
金额:
$0.15万
依托单位国家:
美国
项目类别:
财政年份:
2008
资助国家:
美国
项目状态:
已结题
起止时间:
2008-04-01 至 2008-05-31
关键词:
Botulinum ToxinsBrain imagingClinicalComputer Retrieval of Information on Scientific Projects DatabaseDystoniaEnrollmentFocal DystoniasFunctional disorderFundingGenesGenetic PolymorphismGenotypeGrantInjection of therapeutic agentInstitutionMeasuresParticipantPathogenesisPhenotypePurposeResearchResearch PersonnelResourcesRoleSourceUnited States National Institutes of Healthresponse
中文摘要
这个子项目是许多研究子项目中利用
资源由NIH/NCRR资助的中心拨款提供。子项目和
调查员(PI)可能从NIH的另一个来源获得了主要资金,
并因此可以在其他清晰的条目中表示。列出的机构是
该中心不一定是调查人员的机构。
本研究的目的是通过临床检查、脑成像检查和对肉毒毒素注射的反应,研究与肌张力障碍的发病机制或病理生理学相关的基因的特定多态性对局灶性肌张力障碍表型的影响。预计有360名参与者:160名患有局灶性肌张力障碍的参与者和200名健康对照参与者。
英文摘要
This subproject is one of many research subprojects utilizing the
resources provided by a Center grant funded by NIH/NCRR. The subproject and
investigator (PI) may have received primary funding from another NIH source,
and thus could be represented in other CRISP entries. The institution listed is
for the Center, which is not necessarily the institution for the investigator.
The purpose of this study is to investigate the role of specific polymorphisms in genes associated with the pathogenesis or pathophysiology of dystonia on the phenotype of focal dystonias, as measured by clinical exam, brain imaging studies and response to botulinum toxin injections. Anticipated enrollment is 360 participants: 160 participants who have focal dystonia and 200 healthy control participants.
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专著(0)
科研奖励(0)
会议论文
Genetic Variants in Craniofacial Dystonias
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批准号:10364887
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项目类别:
-
资助金额:$61.88万
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财政年份:2022
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负责人:NUTAN SHARMA
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依托单位:
Genetic Variants in Craniofacial Dystonias
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批准号:10686185
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项目类别:
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资助金额:$60.18万
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财政年份:2022
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负责人:NUTAN SHARMA
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依托单位:
Natural history study of x-linked Dystonia Parkinsonism
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批准号:10181089
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项目类别:
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资助金额:$21.0万
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财政年份:2020
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负责人:NUTAN SHARMA
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依托单位:
Natural history study of x-linked Dystonia Parkinsonism
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批准号:10053483
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项目类别:
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资助金额:$21.0万
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财政年份:2020
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负责人:NUTAN SHARMA
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依托单位:
THE DYT1 MUTATION IN DYSTONIA
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批准号:6613663
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项目类别:
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资助金额:$17.06万
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财政年份:2003
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负责人:NUTAN SHARMA
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依托单位:
THE ROLE OF THE DYT1 MUTATION IN DYSTONIA
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批准号:6740863
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项目类别:
-
资助金额:$17.06万
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财政年份:2003
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负责人:NUTAN SHARMA
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依托单位:
THE ROLE OF THE DYT1 MUTATION IN DYSTONIA
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批准号:6848881
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项目类别:
-
资助金额:$17.06万
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财政年份:2003
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负责人:NUTAN SHARMA
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依托单位:
THE ROLE OF THE DYT1 MUTATION IN DYSTONIA
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批准号:7022189
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项目类别:
-
资助金额:$17.06万
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财政年份:2003
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负责人:NUTAN SHARMA
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依托单位:
Role of DYT1 Mutation in Dystonia
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批准号:7196417
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项目类别:
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资助金额:$17.06万
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财政年份:2003
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负责人:NUTAN SHARMA
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依托单位:
Clinical Core
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批准号:8149948
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项目类别:
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资助金额:$39.0万
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财政年份:--
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负责人:NUTAN SHARMA
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依托单位:
Core B Clinical Core
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批准号:9085424
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项目类别:
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资助金额:$30.15万
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财政年份:--
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负责人:NUTAN SHARMA
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依托单位:
Clinical Core
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批准号:7798806
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项目类别:
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资助金额:$32.13万
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财政年份:--
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负责人:NUTAN SHARMA
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依托单位:
Core B Clinical Core
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批准号:8854419
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项目类别:
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资助金额:$30.15万
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财政年份:--
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负责人:NUTAN SHARMA
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依托单位:
Clinical Core
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批准号:8301696
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项目类别:
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资助金额:$39.0万
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财政年份:--
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负责人:NUTAN SHARMA
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依托单位:
Clinical Core
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批准号:8378369
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项目类别:
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资助金额:$37.93万
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财政年份:--
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负责人:NUTAN SHARMA
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依托单位:
Clinical Core
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批准号:8512804
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项目类别:
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资助金额:$36.6万
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财政年份:--
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负责人:NUTAN SHARMA
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依托单位:
海外基金