VALIDATION OF SELF-REPORT TOOL TO SCREEN FOR PERIODONTAL DISEASE AMONG PREGNANT

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 目的：1.验证自我报告工具在孕妇牙周病筛查中的应用 2.比较有牙周病和无牙周病的女性对口腔病原体的炎症反应。 参与者：在北卡罗来纳大学S诊所接受护理的孕妇 程序(方法)：将在产前检查期间招募符合条件的妇女。同意参与的女性将完成一份旨在筛查牙周病存在的问卷。在完成问卷的14天内，登记的妇女将接受标准化的牙周健康检查，以确定临床牙周病的存在和程度。在牙周健康检查时，将收集和储存牙周沟液和菌斑样本，以供将来分析。妇女还将被要求提供静脉血样本，以检查对口腔病原体的炎症反应。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Purposes: 1. To validate the use of a self report tool to screen for periodontal disease among pregnant women 2. To compare inflammatory responses to oral pathogens between women with and without periodontal disease. Participants: Pregnant women receiving care at the University of North Carolina Women s Clinic Procedures (methods): Eligible women will be recruited during prenatal care visits. Women who agree to participate will complete a questionnaire designed to screen for presence of periodontal disease. Within 14 days of completion of the questionnaire, enrolled women will undergo a standardized periodontal health exam to determine presence and extent of clinical periodontal disease. At the time of the periodontal health exam, gingival crevicular fluid and plaque specimens will be collected and stored for future analyses. Women will also be asked to provide a sample of venous blood to examine for inflammatory responses to oral pathogens.