CONT PSTV AIRWAY PRESS&INSLN SENSITIZATION W/ROSIG ON ERECTILE DYSFNCTN W/APNEA

继续 PSTV 气道新闻

• 批准号: 7719477
• 负责人: Margaret E Wierman
• 金额: $ 0.02万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-04-01 至 2008-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7719477
• 关键词: Affect; Apnea; Computer Retrieval of Information on Scientific Projects Database; Continuous Positive Airway Pressure; Drug usage; Erectile dysfunction; Funding; Grant; Hormones; Institution; Insulin; Insulin Resistance; Non-Insulin-Dependent Diabetes Mellitus; Obstructive Sleep Apnea; Patient Care; Patients; Purpose; Research; Research Personnel; Resources; Sex Functioning; Sleep Apnea Syndromes; Source; Standards of Weights and Measures; United States National Institutes of Health; improved

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to see how obstructive sleep apnea affects erectile function and hormone levels. We are looking at insulin resistance, an underlying cause of type 2 diabetes. Insulin resistance occurs when the body fails to respond properly to the insulin it already produces. This study is examining whether people who have obstructive sleep apnea have insulin resistance that may be worsening their sexual function. We will be treating all patients with continuous positive airway pressure, the standard of care for patients with sleep apnea. In addition, half the patients will receive a drug used initially in the treatment of Type 2 diabetes that helps the body become more sensitive to insulin. We hope that it will improve erectile dysfunction as well.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 这项研究的目的是了解阻塞性睡眠呼吸暂停如何影响勃起功能和激素水平。 我们正在研究胰岛素抵抗，这是2型糖尿病的一个潜在原因。 当身体不能对已经产生的胰岛素做出适当反应时，就会发生胰岛素抵抗。 这项研究正在调查患有阻塞性睡眠呼吸暂停的人是否有胰岛素抵抗，这可能会使他们的性功能恶化。我们将对所有患者进行持续气道正压通气治疗，这是睡眠呼吸暂停患者的标准治疗。 此外，一半的患者将接受最初用于治疗2型糖尿病的药物，帮助身体对胰岛素更加敏感。 我们希望它也能改善勃起功能障碍。