Ultra-wide Field-of-View Endoscope for White Light and Narrow Band Imaging

描述(申请人提供)：内窥镜可视化对于微创手术至关重要。然而，目前内窥镜成像技术的已知局限性包括视野有限、特异性和敏感性不令人满意。InterScience在此提出了一种具有白光和窄带成像能力的全方位内窥镜系统，该系统基于我们获得专利和正在申请专利的C-ViewTM光学技术，允许围绕光轴的宽视野高达120度，以及360度全景(3@立体立体角)。除了正常的白光观察外，该系统还提供窄带成像功能(以窄的红、绿或蓝色光带照明)，旨在帮助早期发现微小病变，如癌症和手术前对病变区域的准确诊断。它还将提供增强的图像，显示粘膜表面病变和毛细血管的特征性变化，以及粘膜和粘膜深处的血管轻微增厚-通过控制使用的光的波长。提出的内窥镜具有前所未有的大视野，无需图像配准即可极大地提高成像覆盖率和一致性，并可增加图像的特异性和操作的彻底性，同时最大限度地减少手术时间和各种斜面内窥镜在术中互换对患者造成的创伤。第一阶段的工作包括成像光学设计、照明设计、初步电气设计、图像处理算法开发，以及一些现成组件的研究和测试。与公共卫生相关：项目简介内窥镜具有前所未有的视野(大于半球)，以及白光和窄带成像功能，将为临床医生提供更具体的信息，用于异常诊断，并将比现有的内窥镜系统更有利于辅助微创手术。

DESCRIPTION (provided by applicant): Endoscopic visualization is of primary importance for minimally invasive procedures. However, known limitations of current endoscopic imaging technology include the limited field-of-view, and unsatisfactory specificity and sensitivity. InterScience hereby proposes an omnidirectional endoscopic system with both white light and narrow band imaging capability, based on our patented and patent pending C-ViewTM optical technology, allowing a broad field-of-view up to 120 degrees about the optical axis and 360 degrees panoramically (3@ steradian solid angle). In addition to normal white light observation, the proposed system offers narrow band imaging function (illuminated with narrowed red, green, or blue bands of light), targeting to assist the early detection of minute lesions such as cancer and preoperative accurate diagnosis of diseased areas. It will also deliver enhanced images of characteristic changes of lesions and capillary vessels in the mucosal surface, and slight thickening of the mucosa as well as vessels deep in the mucosa - by controlling the wavelength of light used. The unprecedented wide field- of-view of the proposed endoscope would greatly improve imaging coverage and consistency without image registration, as well as increase the specificity and procedure thoroughness while minimizing procedure time and trauma to the patient induced by intra-procedural swapping of various beveled scopes. The Phase I efforts include imaging optics design, illumination design, preliminary electrical designs, image processing algorithm development, plus the studies and tests of some off-the-shelf components. PUBLIC HEALTH RELEVANCE: Project Narrative The endoscope with an unprecedented field-of-view (larger than a hemisphere), and white light and narrow band imaging functions will present much more specific information to clinicians for abnormalities diagnosis, and will be more advantageous to assist minimum invasive procedures than currently existing endoscopic systems.