ACUTE HIV INFECTION AND EARLY DISEASE RESEARCH PROGRAM (AIEDRP) CORE01 DATA PROT

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 这项研究是为了了解人体在艾滋病毒感染早期的反应，以及人体在几年内如何随着艾滋病毒感染而变化，无论是否接受抗逆转录病毒药物和/或免疫治疗。 更具体地说，AIEDRP数据库研究将做以下工作： ¿ 描述本研究中的受试者是否出现HIV-1相关问题 ¿ 检查哪些类型的副作用可能会发生在治疗最近的艾滋病毒感染; ¿ 跟踪在最近的艾滋病毒感染中确定的接受治疗和未接受治疗的人血液中的艾滋病毒数量 ¿ 比较哪些因素决定治疗和未治疗人群中免疫血细胞（T细胞）的数量和HIV的数量，并描述治疗和未治疗人群中免疫细胞如何随时间变化; ¿ 评估在最近感染艾滋病毒期间发现的接受治疗和未接受治疗的人的因素，这些因素可能会影响他们的疾病过程和他们对治疗的长期反应。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This study is being done to learn how the body responds early in the HIV infection period and how the body changes with HIV infection over several years whether or not someone is treated with antiretroviral drugs and/or immune-based therapies. More specifically the AIEDRP database study will do the following: ¿ Describe whether or not people in this study develop HIV-1 related problems ¿ Examine what kinds of side effects may occur during treatment of recent HIV infection; ¿ Follow the amount of HIV in the blood of those treated and untreated people identified during recent HIV infection ¿ Compare what factors determine the amount of immune blood cells (T cells) and the amount of HIV in treated and untreated people and describe how the immune cells may vary over time in treated and untreated people; ¿ Evaluate factors in treated and untreated people identified during their recent HIV infection that may influence the course of their disease and their response to treatment over the long-term.