ACUTE HIV INFECTION AND EARLY DISEASE RESEARCH PROGRAM (AIEDRP) CORE01 DATA PROT

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 进行这项研究是为了了解人体在艾滋病毒感染期早期如何反应，以及在几年内身体如何随着艾滋病毒感染而变化，无论某人是否接受抗逆转录病毒药物和/或基于免疫的治疗。更具体地说，AIEDRP数据库研究将做以下工作： ？描述这项研究中的人是否会出现与HIV-1相关的问题 ？检查近期艾滋病毒感染的治疗过程中可能出现的副作用； ？跟踪那些在最近感染艾滋病毒期间发现的接受治疗和未接受治疗的人的血液中艾滋病毒的量 ？比较哪些因素决定了治疗和未治疗人群中免疫血细胞(T细胞)的数量和HIV的数量，并描述了免疫细胞在治疗和未治疗人群中随时间的变化； 评估在最近感染艾滋病毒期间发现的可能影响其病程和长期治疗反应的已治疗和未接受治疗的人的因素。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This study is being done to learn how the body responds early in the HIV infection period and how the body changes with HIV infection over several years whether or not someone is treated with antiretroviral drugs and/or immune-based therapies. More specifically the AIEDRP database study will do the following: ¿ Describe whether or not people in this study develop HIV-1 related problems ¿ Examine what kinds of side effects may occur during treatment of recent HIV infection; ¿ Follow the amount of HIV in the blood of those treated and untreated people identified during recent HIV infection ¿ Compare what factors determine the amount of immune blood cells (T cells) and the amount of HIV in treated and untreated people and describe how the immune cells may vary over time in treated and untreated people; ¿ Evaluate factors in treated and untreated people identified during their recent HIV infection that may influence the course of their disease and their response to treatment over the long-term.