CLINICAL TRIAL: HOMOCYSTEINE TRIAL

临床试验：同型半胱氨酸试验

• 批准号: 7724992
• 负责人: RUTH MULNARD MCCARGAR
• 金额: $ 0.05万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-12-01 至 2008-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7724992
• 关键词: Aging; Alzheimer' s Disease; Clinical Trials; Computer Retrieval of Information on Scientific Projects Database; Folate; Funding; Grant; Homocysteine; Homocystine; Institutes; Institution; Patients; Placebos; Randomized; Research; Research Personnel; Resources; Source; United States National Institutes of Health; Vitamin B 12; Vitamin B6

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This is a clinical trial supported by the National Institute on Aging for an eighteen month period of exposure in which patients with Alzheimer's disease are randomized to receive a combination of vitamin B6, vitamin B12, and folate versus placebo to evaluate the ability of these agents to delay the progression of Alzheimer's disease (via a homocysteine-lowering mechanism).

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 这是一项由国家老龄化研究所支持的临床试验，为期18个月，其中阿尔茨海默病患者随机接受维生素B6，维生素B12和叶酸的组合与安慰剂，以评估这些药物延迟阿尔茨海默病进展的能力（通过降低同型半胱氨酸的机制）。