Sexuality, Aging and Heart Disease: Translating from Population to Patient

性、衰老和心脏病：从人群到患者的转变

基本信息

批准号：
7731711
负责人：
Stacy Tessler Lindau
金额：
$ 19.2万
依托单位：
UNIVERSITY OF CHICAGO
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
起止时间：
2009-09-30 至 2013-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7731711
关键词：
Address Affect Age Aging American Arousal Attitude Award Behavior Cardiology Cardiovascular Diseases Caring Case-Control Studies Cause of Death Chicago Chronic Disease Clinical Clinical Trials Clinical Trials Design Collaborations Communication Communities Comorbidity Complex Data Data Collection Dementia Development Diagnosis Disease Distress Effectiveness of Interventions Elderly Emotional Enrollment Ensure Environment Evaluation Feasibility Studies Feeling Female Frequencies Future Geriatrics Gerontology Goals Gynecologist Health Health Status Healthcare Heart Diseases Hospitalization Human Individual Intervention Intervention Studies Interview K-Series Research Career Programs Knowledge Lead Leadership Level of Evidence Life Link Literature Malignant Neoplasms Masturbation Medical Mentors Mentorship Methods Myocardial Infarction Operative Surgical Procedures Oral Sex Orgasm Outcome Patients Pattern Phase Physicians Physiological Pilot Projects Population Population Research Positioning Attribute Prevalence Prevention Prevention approach Qualitative Methods Quality of Care Quality of life Randomized Recording of previous events Recovery Relaxation Research Research Design Research Methodology Research Personnel Risk Risk Adjustment Scientist Severity of illness Sex Behavior Sex Functioning Sexual Dysfunction Sexual Health Sexuality Societies Specialist Spouses Staging Stratification Subgroup Surveys Testing Training Translating Universities Vagina Woman Work career clinically relevant cohort design erection evidence base experience high risk improved interest male medical attention men older men older women patient oriented pleasure population based prevent programs prospective psychosocial resilience response satisfaction sex sexually active skills skills training social success tool tool development treatment as usual willingness young adult

项目摘要

DESCRIPTION (provided by applicant): A Beeson Career Development Award is proposed by the University of Chicago to advance the candidate, Stacy Lindau, MD, to productive, independent investigatorship and leadership in clinically-relevant aging research. Her long-term career goal is to fundamentally alter the approach to and outlook for older adult sexuality by designing effective and disease-focused clinical interventions. An evidence base does not yet exist for disease-specific approaches to prevention and management of sexual problems among older adults with chronic illness, especially women. Dr. Lindau's work, to date, has been mainly in collaboration with social scientists using population-based survey research methods. This research establishes that many older adults are sexually active, sexual problems are highly prevalent and that physician communication with older adults about sexuality (particularly women) infrequently occurs. As a gynecologist researcher with clinical experience in treatment of female sexual problems, Dr. Lindau's immediate career goal is to move her gerosexuality research focus from population to patient. Specifically, she aims to identify how myocardial infarction in older women affects sexuality, who is most at risk, and what can be done to prevent and ameliorate negative sexual sequelae following an Ml. She will do this using population-based and clinical observational data, qualitative methods, and by carrying out a clinical trial feasibility study. Moving from population to patient requires substantial new, training, skills and research experience, including mentored training in clinical cardiology and geriatrics, clinical trials design and implementation, comorbidity and disease severity adjustment, risk stratification tool development, and analytic methods for assessing clinical outcomes and intervention effectiveness. With these new skills, Dr. Lindau is poised to become a uniquely cross-trained, translational researcher in aging whose work and leadership can advance both gerontology and geriatrics approaches to older adult sexuality. An ambitious four year plan is proposed, appropriate to Dr. Lindau's level of experience, in an excellent research environment. Mentorship will help ensure Dr. Lindau's success and will facilitate development of productive, lasting collaborations with geriatricians and other clinical specialists. The Beeson Award will link Dr. Lindau and her career to the premier network of clinical aging researchers and will position her to lead and inspire others in aging research. RELEVANCE: Sexual activity and function are strongly associated with overall health in later life, yet medical attention to sexual concerns of older adults is dismal. This research will provide an evidence base for design and evaluation of interventions to prevent, identify and intervene upon a highly prevalent, but largely ignored, spectrum of distressing problems experienced by older adults with common illnesses.

描述（由申请人提供）：芝加哥大学提出了Beeson职业发展奖，以推动候选人Stacy Lindau，医学博士，在临床上与临床相关的衰老研究中的生产性，独立的研究人员和领导力。她的长期职业目标是通过设计有效和以疾病为中心的临床干预措施从根本上改变成人性生活的方法和前景。尚不存在针对疾病特异性方法预防和管理性问题的证据基础，特别是慢性病，尤其是女性。迄今为止，Lindau博士的工作主要是使用基于人群的调查研究方法与社会科学家合作的。这项研究确定，许多老年人具有性活跃，性问题非常普遍，并且医生与老年人就性行为（尤其是女性）的沟通很少发生。作为一名具有临床治疗女性性问题的临床经验的妇科医生研究人员，琳道博士的直接职业目标是将她的老年恋研究重点从人口转移到患者。具体而言，她的目标是确定老年妇女的心肌梗塞如何影响性行为，最有风险的人以及在ML之后可以采取什么措施来预防和改善负面性后遗症。她将使用基于人群和临床观察数据，定性方法以及进行临床试验可行性研究来做到这一点。从人口转变为患者需要大量的新，培训，技能和研究经验，包括临床心脏病学和老年病的指导培训，临床试验设计和实施，合并症和疾病严重性调整，风险分层工具的开发以及评估临床成果和干预效果的分析方法。凭借这些新技能，琳达博士有望成为一名独特的交叉培训，翻译成老化的研究人员，他们的工作和领导能力可以推动老年病和老年医学家对老年人性行为的方法。在出色的研究环境中，提出了一个雄心勃勃的四年计划，适合林道博士的经验水平。指导将有助于确保Lindau博士的成功，并促进与老年医生和其他临床专家的生产，持久合作的发展。 Beeson Award将Lindau博士及其职业生涯与临床老龄化研究人员的主要网络联系起来，并将她定位以领导和激发其他人的衰老研究。相关性：性活动和功能与以后的生活中的整体健康密切相关，但是医疗关注老年人的性关注是惨淡的。这项研究将为设计和评估干预措施的设计和评估提供证据基础，以防止，识别和干预高度普遍但很大程度上被忽略的痛苦问题，这些问题是常见疾病的老年人所经历的令人困扰的问题。