Sexuality, Aging and Heart Disease: Translating from Population to Patient

性、衰老和心脏病：从人群到患者的转变

• 批准号: 7731711
• 负责人: Stacy Tessler Lindau
• 金额: $ 19.2万
• 依托单位: UNIVERSITY OF CHICAGO
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-30 至 2013-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7731711
• 关键词: Address; Affect; Age; Aging; American; Arousal; Attitude; Award; Behavior; Cardiology; Cardiovascular Diseases; Caring; Case-Control Studies; Cause of Death; Chicago; Chronic Disease; Clinical; Clinical Trials; Clinical Trials Design; Collaborations; Communication; Communities; Comorbidity; Complex; Data; Data Collection; Dementia; Development; Diagnosis; Disease; Distress; Effectiveness of Interventions; Elderly; Emotional; Enrollment; Ensure; Environment; Evaluation; Feasibility Studies; Feeling; Female; Frequencies; Future; Geriatrics; Gerontology; Goals; Gynecologist; Health; Health Status; Healthcare; Heart Diseases; Hospitalization; Human; Individual; Intervention; Intervention Studies; Interview; K-Series Research Career Programs; Knowledge; Lead; Leadership; Level of Evidence; Life; Link; Literature; Malignant Neoplasms; Masturbation; Medical; Mentors; Mentorship; Methods; Myocardial Infarction; Operative Surgical Procedures; Oral Sex; Orgasm; Outcome; Patients; Pattern; Phase; Physicians; Physiological; Pilot Projects; Population; Population Research; Positioning Attribute; Prevalence; Prevention; Prevention approach; Qualitative Methods; Quality of Care; Quality of life; Randomized; Recording of previous events; Recovery; Relaxation; Research; Research Design; Research Methodology; Research Personnel; Risk; Risk Adjustment; Scientist; Severity of illness; Sex Behavior; Sex Functioning; Sexual Dysfunction; Sexual Health; Sexuality; Societies; Specialist; Spouses; Staging; Stratification; Subgroup; Surveys; Testing; Training; Translating; Universities; Vagina; Woman; Work; career; clinically relevant; cohort; design; erection; evidence base; experience; high risk; improved; interest; male; medical attention; men; older men; older women; patient oriented; pleasure; population based; prevent; programs; prospective; psychosocial; resilience; response; satisfaction; sex; sexually active; skills; skills training; social; success; tool; tool development; treatment as usual; willingness; young adult

DESCRIPTION (provided by applicant): A Beeson Career Development Award is proposed by the University of Chicago to advance the candidate, Stacy Lindau, MD, to productive, independent investigatorship and leadership in clinically-relevant aging research. Her long-term career goal is to fundamentally alter the approach to and outlook for older adult sexuality by designing effective and disease-focused clinical interventions. An evidence base does not yet exist for disease-specific approaches to prevention and management of sexual problems among older adults with chronic illness, especially women. Dr. Lindau's work, to date, has been mainly in collaboration with social scientists using population-based survey research methods. This research establishes that many older adults are sexually active, sexual problems are highly prevalent and that physician communication with older adults about sexuality (particularly women) infrequently occurs. As a gynecologist researcher with clinical experience in treatment of female sexual problems, Dr. Lindau's immediate career goal is to move her gerosexuality research focus from population to patient. Specifically, she aims to identify how myocardial infarction in older women affects sexuality, who is most at risk, and what can be done to prevent and ameliorate negative sexual sequelae following an Ml. She will do this using population-based and clinical observational data, qualitative methods, and by carrying out a clinical trial feasibility study. Moving from population to patient requires substantial new, training, skills and research experience, including mentored training in clinical cardiology and geriatrics, clinical trials design and implementation, comorbidity and disease severity adjustment, risk stratification tool development, and analytic methods for assessing clinical outcomes and intervention effectiveness. With these new skills, Dr. Lindau is poised to become a uniquely cross-trained, translational researcher in aging whose work and leadership can advance both gerontology and geriatrics approaches to older adult sexuality. An ambitious four year plan is proposed, appropriate to Dr. Lindau's level of experience, in an excellent research environment. Mentorship will help ensure Dr. Lindau's success and will facilitate development of productive, lasting collaborations with geriatricians and other clinical specialists. The Beeson Award will link Dr. Lindau and her career to the premier network of clinical aging researchers and will position her to lead and inspire others in aging research. RELEVANCE: Sexual activity and function are strongly associated with overall health in later life, yet medical attention to sexual concerns of older adults is dismal. This research will provide an evidence base for design and evaluation of interventions to prevent, identify and intervene upon a highly prevalent, but largely ignored, spectrum of distressing problems experienced by older adults with common illnesses.

描述（由申请人提供）：一个比森职业发展奖是由芝加哥大学提出的，以推进候选人，斯泰西林道，医学博士，生产力，独立的咨询和领导在临床相关的老龄化研究。她的长期职业目标是通过设计有效和以疾病为重点的临床干预措施，从根本上改变老年人性行为的方法和前景。目前还没有证据基础来证明针对特定疾病的方法可以预防和管理患有慢性病的老年人，特别是妇女的性问题。 博士迄今为止，林道的工作主要是与社会科学家合作，使用基于人口的调查研究方法。这项研究证实，许多老年人性活跃，性问题非常普遍，医生与老年人（特别是女性）就性问题进行沟通的情况很少发生。 作为一名在女性性问题治疗方面具有临床经验的妇科研究人员，林道博士的直接职业目标是将她的老年性研究重点从人群转移到患者。具体而言，她的目标是确定老年妇女心肌梗死如何影响性行为，谁是最危险的，以及可以做些什么来预防和改善MI后的负面性后遗症。她将使用基于人群和临床观察数据，定性方法和进行临床试验可行性研究来实现这一目标。从人群转移到患者需要大量的新的培训，技能和研究经验，包括临床心脏病学和老年病学的指导培训，临床试验设计和实施，合并症和疾病严重程度调整，风险分层工具开发以及评估临床结局和干预有效性的分析方法。林道准备成为一个独特的交叉训练，在老龄化的翻译研究人员，其工作和领导可以推进老年学和老年医学方法老年成人性行为。 提出了一个雄心勃勃的四年计划，适合博士林道的经验水平，在一个良好的研究环境。导师制将有助于确保林道博士的成功，并将促进与老年病学家和其他临床专家的富有成效的持久合作。Beeson奖将Lindau博士和她的职业生涯与临床衰老研究人员的首要网络联系起来，并将使她能够领导和激励其他人进行衰老研究。 相关性：性活动和性功能与晚年的整体健康密切相关，但对老年人性问题的医疗关注令人沮丧。这项研究将为设计和评估干预措施提供证据基础，以预防，识别和干预一个高度普遍，但在很大程度上被忽视的，由患有常见疾病的老年人所经历的痛苦问题。