APOE RECEPTOR SPLICING, GENETICS, AND AD
APOE RECEPTOR SPLICING, GENETICS, AND AD
批准号:
7580202
负责人:
Steven Estus
金额:
$30.43万
依托单位国家:
美国
项目类别:
财政年份:
2009
资助国家:
美国
项目状态:
已结题
起止时间:
2009-08-15 至 2014-06-30
关键词:
AllelesAlzheimer&aposs DiseaseApolipoprotein EArtsAutopsyBiological AssayBiologyBlood - brain barrier anatomyBrainCell surfaceCellsCleaved cellCollaborationsComplexComputer SimulationComputer softwareDNADataDiseaseDisease AssociationEarly DiagnosisEmployee StrikesEnhancersEtiologyEvaluationExonsExtracellular DomainExtracellular SpaceFamily memberFoundationsGene ExpressionGenerationsGeneticGenetic PolymorphismGenetic VariationGenotypeHaplotypesHumanIn VitroIndividualKentuckyLDL-Receptor Related Protein 1LengthLinkMediatingMessenger RNANerve DegenerationPhasePopulationPredispositionProtein IsoformsProteinsProteolysisProteomicsRNA SplicingReagentRelative (related person)Religion and SpiritualityResearchRestRoleSamplingSingle Nucleotide PolymorphismSiteStagingTestingTherapeutic UsesTransmembrane DomainUniversitiesVariantWorkapolipoprotein E receptor 2apolipoprotein E-4basebrain tissuegenetic associationgenetic risk factorgenetic variantin vivoinnovationinsightmalemembernovelpopulation basedprogramsprotein expressionreceptorreceptor expressionreceptor functionstable cell linesuccesssugar
中文摘要
点击翻译按钮获取中文摘要
英文摘要
these studies are significant and innovative because they
have strong relevance to our understanding of the possible mechanistic etiology of AD, potentially
facilitating therapy, and to AD genetics, facilitating early diagnosis and treatment.
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财政年份:2014
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Translating CD33 genetic mechanism into a novel Alzheimers therapeutic
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资助金额:$30.75万
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财政年份:2014
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LDLR Genetics, Splicing and AD Risk
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批准号:7272847
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资助金额:$26.28万
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LDLR Genetics, Splicing and AD Risk
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资助金额:$28.22万
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LDLR Genetics, Splicing and AD Risk
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批准号:7440187
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资助金额:$25.75万
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UPA Polymorphisms as a Differential Risk Factor for AD
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资助金额:$25.34万
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财政年份:2002
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Urokinase-type plasminogen activator and Alzheimer's
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财政年份:2002
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依托单位:
Urokinase-type plasminogen activator/Alzheimer's Disease
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批准号:6550671
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项目类别:
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资助金额:$14.35万
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财政年份:2002
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依托单位:
UPA Polymorphisms as a Differential Risk Factor for AD
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财政年份:2002
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依托单位:
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财政年份:1996
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依托单位:
C-JUN AND AMYLOID-INDUCED APOPTOSIS
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财政年份:1996
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财政年份:1995
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依托单位:
C JUN, C FOS AND NEURONAL PROGRAMMED CELL DEATH
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