ECG-GATED 16-SLICE CTCA: COMPARISON WITH CATHETER CORONARY ANGIOGRAPHY

心电门控 16 层 CTCA：与导管冠状动脉造影的比较

• 批准号: 7603742
• 负责人: SMITA S PATEL
• 金额: $ 0.14万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-03-01 至 2007-09-16
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7603742
• 关键词: Accounting; Acute; Age; Age-Years; Angioplasty; Blood flow; Cardiac; Cardiac Catheterization Procedures; Catheters; Cause of Death; Cessation of life; Chest; Chest Pain; Computer Retrieval of Information on Scientific Projects Database; Condition; Coronary Angiography; Coronary Arteriosclerosis; Coronary Artery Bypass; Coronary artery; Death Rate; Diagnosis; Diagnostic; Dose; Enrollment; Event; Funding; Goals; Grant; Heart; Heart Diseases; Image; Imaging Device; Individual; Institution; Intervention; Invasive; Lead; Michigan; Modality; Myocardial Infarction; Numbers; Pain; Patients; Physicians; Placement; Procedures; Radiation; Research; Research Personnel; Resources; Risk; Risk Factors; Schedule; Slice; Source; Stents; Techniques; Testing; United States; United States National Institutes of Health; Woman; X-Ray Computed Tomography; men; statistics; tool

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Disease of the coronary arteries, which may ultimately lead to a heart attack, is the leading cause of death in the United States, accounting for 30% of all deaths in the United States in the year 2000 (NIH statistics). The state of Michigan has the 4th highest age-adjusted death rate for CAD in USA. Catheter coronary angiography is currently the best diagnostic tool available to detect blood flow problems in the major vessels of the heart, however, it is a invasive procedure with many associated risks. We would like to determine if CT Coronary Angiography using the newer faster 64-slice CT scanner (a CAT Scan of your heart and major arteries of the heart) is an accurate imaging modality for diagnosing coronary artery disease. This study hopes to show that by using new CT scanning techniques we will be able to diagnose heart conditions accurately, and more safely, than heart catheterization. Men and women 18 years of age or older who are scheduled to have a heart catheterization by their physician can participate in this study. We will enroll subjects both who have had or have not had a previous heart intervention such as angioplasty, stent placement or coronary artery bypass surgery. If CT coronary angiography proves to be a robust imaging tool, it may become useful both in patients with chest pain, and atypical chest pain, when it is difficult to know whether the pain in the chest is originating from the heart or not. Potential advantages of CT include decreased radiation dose vs cardiac catheterization and that a greater number of people with possible heart disease may opt for this non-invasive test. The test may also prove to be less expensive than cardiac catheterization. If CT is accurate for the diagnosis of coronary artery disease, it may be possible to use CT to screen asymptomatic individuals with a high risk factor profile for coronary artery disease; with the long term goal of reducing acute cardiac events and death from coronary artery disease.'

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 冠状动脉疾病最终可能导致心脏病发作，是美国死亡的主要原因，占2000年美国所有死亡人数的30％（NIH统计）。密歇根州在美国的CAD是年龄调整后的第四高。目前，导管冠状动脉血管造影是检测心脏主要血管中血流问题的最佳诊断工具，但是，这是一种具有许多相关风险的侵入性手术。我们想确定使用更快的64片CT扫描仪（您心脏的猫扫描和心脏的主要动脉）使用CT冠状动脉血管造影是一种准确的成像方式，用于诊断冠状动脉疾病。这项研究希望表明，通过使用新的CT扫描技术，我们将能够与心脏导管插入术相比准确，更安全地诊断心脏状况。 18岁或以上的男性和女性计划由医生进行心脏导管插入术，可以参加这项研究。我们将招募曾经或没有以前的心脏干预的受试者，例如血管成形术，支架放置或冠状动脉搭桥手术。如果CT冠状动脉造影被证明是一种健壮的成像工具，那么当难以知道胸部的疼痛是否起源于心脏时，它在胸痛和非典型胸痛的患者中可能变得有用。 CT的潜在优势包括降低辐射剂量与心脏导管插入术，更多可能的心脏病患者可能会选择这种非侵入性测试。该测试也可能比心脏导管插入术便宜。如果CT对于诊断冠状动脉疾病的诊断是准确的，则可以使用CT来筛选无症状的冠状动脉疾病危险因素概况的无症状患者；长期目标是减少急性心脏事件和冠状动脉疾病死亡。