ACTIVITY PACING AND SYMPTOMS IN OLDER ADULTS WITH OSTEOARTHRITIS

患有骨关节炎的老年人的活动节奏和症状

• 批准号: 7603812
• 负责人: Susan Kay Murphy
• 金额: $ 1.67万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-03-01 至 2007-09-16
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7603812
• 关键词: Affect; Computer Retrieval of Information on Scientific Projects Database; Computers; Consent Forms; Control Groups; Daily; Data; Databases; Degenerative polyarthritis; Devices; Elderly; Equilibrium; Fatigue; Female; Frequencies; Funding; Gait; Grant; Hip Osteoarthritis; Hip region structure; Institution; Instruction; Knee; Knee Osteoarthritis; Life; Lower Extremity; Measurement; Methods; Michigan; Names; Numbers; Pain; Participant; Performance; Physical Function; Principal Investigator; Recruitment Activity; Research; Research Personnel; Resources; Respondent; Rest; Score; Screening procedure; Source; Symptoms; Testing; Thinking; Time; United States National Institutes of Health; Universities; Variant; Woman; Wrist; aged; day; demographics; disability; experience; interest; older women; pain adaptation; programs; response

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Osteoarthritis is a leading cause of disability among older adults. Lower extremity osteoarthritis (LE-OA) is associated with symptoms of pain and fatigue that affect activity performance. Little is known about how older adults with LE-OA experience these symptoms in everyday life or the adaptations they make in response even though these adaptations are thought to influence disability. This project will investigate the relationship between adaptation and pain and fatigue symptoms by focusing on one key adaptation, activity pacing (e.g. use of strategies that balance activities with rest) and by using a real-time measurement method (e.g. acti-score devices). Sixty females aged 55-80 will be recruited from the Research Participant Program of the University of Michigan s Geriatric Center: 40 with pain-limiting LE-OA and 20 healthy controls. All interested respondents who come for screening will be informed about the study and asked to sign the consent form. Knee or hip osteoarthritis will be determined first through radiographic confirmation. Pain-limiting hip or knee osteoarthritis will be determined by having a score of five or greater on the WOMAC pain subscale. Participants will answer basic questions regarding demographics and physical function and will participate in physical performance assessments of gait, strength, and balance. Then participants will receive instruction on wearing the acti-score devices. Devices will be worn on the wrist for five days and participants will be prompted at six time-points throughout the day. At each time-point, participants will input their frequency of using activity pacing and pain and fatigue levels into the device. All data collected will be compiled into computer databases in which participants will only be identified from an ID number. Signed informed consent forms and a master list that matches ID numbers with participant names will be kept in a locked drawer in the principal investigators office. The specific aims of this project are 1) To examine the experience of LE-OA-related symptoms over a five-day period, the diurnal (e.g., daily) variations of pain and fatigue levels of older women with lower extremity OA (LE-OA) will be compared to healthy women controls and 2) To examine the relationship between activity pacing, pain, and fatigue among older women with LE-OA and the control group over a five day testing period.'

这个子项目是许多利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 骨关节炎是老年人残疾的主要原因。下肢骨关节炎（LE-OA）与影响活动能力的疼痛和疲劳症状相关。对于患有LE-OA的老年人在日常生活中如何经历这些症状或他们做出的适应反应知之甚少，即使这些适应被认为会影响残疾。该项目将通过关注一个关键的适应，活动起搏（例如使用平衡活动与休息的策略）和使用实时测量方法（例如活动评分设备）来调查适应与疼痛和疲劳症状之间的关系。将从密歇根大学老年中心的研究参与者计划中招募60名年龄在55-80岁之间的女性：40名患有疼痛限制性LE-OA的女性和20名健康对照者。将告知所有前来进行筛选的感兴趣的受访者有关研究的信息，并要求他们签署知情同意书。膝关节或髋关节骨关节炎将首先通过影像学确认确定。疼痛限制性髋关节或膝关节骨关节炎将通过WOMAC疼痛子量表评分≥ 5分来确定。参与者将回答有关人口统计学和身体功能的基本问题，并将参与步态，力量和平衡的身体表现评估。然后，参与者将收到关于佩戴活动评分设备的指导。设备将戴在手腕上五天，参与者将在一天中的六个时间点得到提示。在每个时间点，参与者将其使用活动起搏的频率以及疼痛和疲劳水平输入到设备中。所有收集到的数据将被编入计算机数据库，在该数据库中，参与者将仅通过身份证号码进行识别。签署的知情同意书和ID编号与受试者姓名匹配的主列表将保存在主要研究者办公室的上锁抽屉中。该项目的具体目标是：1）检查LE-OA相关症状在五天内的经历，昼夜（例如，每日）将患有下肢OA（LE-OA）的老年女性的疼痛和疲劳水平的变化与健康女性对照进行比较，以及2）在五天的测试期内检查患有LE-OA的老年女性和对照组之间的活动起搏、疼痛和疲劳之间的关系。'