RANDOMIZED TRIAL OF RECOMBINANT GM-CSF FOR PATIENTS W/ ACUTE LUNG INJURY
RANDOMIZED TRIAL OF RECOMBINANT GM-CSF FOR PATIENTS W/ ACUTE LUNG INJURY
批准号:
7603750
负责人:
Robert C Hyzy
金额:
$0.16万
依托单位国家:
美国
项目类别:
财政年份:
2007
资助国家:
美国
项目状态:
已结题
起止时间:
2007-03-01 至 2007-09-16
关键词:
Acute Lung InjuryAdult Respiratory Distress SyndromeAnimalsBacteriaBiologicalBreathingCellsCicatrixComputer Retrieval of Information on Scientific Projects DatabaseDiagnosisEnrollmentFundingFutureGrantGranulocyte-Macrophage Colony-Stimulating FactorHealedInfectionInstitutionLifeLungMechanical VentilatorsPatientsPharmaceutical PreparationsPurposeRandomized Controlled Clinical TrialsRecombinantsResearchResearch PersonnelResourcesSourceUnited States Food and Drug AdministrationUnited States National Institutes of Healthcancer therapycancer typefight againsthealinginjuredpreventsargramostim
中文摘要
这个子项目是众多研究子项目之一
英文摘要
This subproject is one of many research subprojects utilizing the
resources provided by a Center grant funded by NIH/NCRR. The subproject and
investigator (PI) may have received primary funding from another NIH source,
and thus could be represented in other CRISP entries. The institution listed is
for the Center, which is not necessarily the institution for the investigator.
Patients diagnosed with a life-threatening illness that has injured your lungs, called acute lung injury or Acute Respiratory Distress Syndrome (ARDS) who have been put on a mechanical ventilator, to help breathe, will be considered for enrollment in the study. The purpose of this study is to find out whether a drug called Sargramostim can help patients with acute lung injury or ARDS. Sargramostim is also known as GM-CSF. Sargramostim has been approved by the FDA to treat complications arising from some types of cancer or cancer treatment, and some studies using animals suggest that it may also help ARDS patients. Sargramostim is a biological compound that is already in the body, especially in the lungs. It is important for keeping lungs healthy. Sargramostim may help injured cells inside the lung heal faster, and it may help lungs fight against bacteria that can cause infections. It may also prevent or decrease scarring in the lungs. This study may help us develop better treatment for patients with ARDS in the future.'
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Clinical Centers (CC) for the NHLBI Prevention and Early Treatment of Acute Lung
-
批准号:8707064
-
项目类别:
-
资助金额:$14.59万
-
财政年份:2014
-
负责人:Robert C Hyzy
-
依托单位:
Clinical Centers (CC) for the NHLBI Prevention and Early Treatment of Acute Lung
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批准号:9926297
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项目类别:
-
资助金额:$40.87万
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财政年份:2014
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负责人:Robert C Hyzy
-
依托单位:
Clinical Centers (CC) for the NHLBI Prevention and Early Treatment of Acute Lung
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批准号:9268039
-
项目类别:
-
资助金额:$40.87万
-
财政年份:2014
-
负责人:Robert C Hyzy
-
依托单位:
Clinical Centers (CC) for the NHLBI Prevention and Early Treatment of Acute Lung
-
批准号:9062500
-
项目类别:
-
资助金额:$40.87万
-
财政年份:2014
-
负责人:Robert C Hyzy
-
依托单位:
OBSERVATIONAL STUDY OF ACUTE LUNG INJURY & ACUTE RESPIRATORY DISTRESS SYNDROME
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批准号:7603766
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项目类别:
-
资助金额:$0.2万
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财政年份:2007
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负责人:Robert C Hyzy
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依托单位:
AN OBSERVATIONAL STUDY OF PATIENTS WITH ACUTE LUNG INJURY AND ACUTE RESPIRATORY
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批准号:7376600
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项目类别:
-
资助金额:$0.36万
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财政年份:2006
-
负责人:Robert C Hyzy
-
依托单位:
Core-- Clinical Core
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批准号:7108655
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项目类别:
-
资助金额:$81.05万
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财政年份:2005
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负责人:Robert C Hyzy
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依托单位:
Core-- Clinical Core
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批准号:6824839
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项目类别:
-
资助金额:$93.33万
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财政年份:2003
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负责人:Robert C Hyzy
-
依托单位:
Core-- Clinical Core
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批准号:7258888
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项目类别:
-
资助金额:$83.49万
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财政年份:--
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负责人:Robert C Hyzy
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依托单位:
Core-- Clinical Core
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批准号:7485735
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项目类别:
-
资助金额:$139.97万
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财政年份:--
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负责人:Robert C Hyzy
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依托单位:
海外基金