CHOLINE, PREGNANCY, AND BRAIN DEVELOPMENT

胆碱、怀孕和大脑发育

• 批准号: 7625513
• 负责人: Steven H Zeisel
• 金额: $ 0.06万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-12-01 至 2007-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7625513
• 关键词: Blood; Brain; Cells; Chemicals; Choline; Computer Retrieval of Information on Scientific Projects Database; Consumption; Development; Diet; Funding; Grant; Human; Human Milk; Institution; Life; Membrane; Memory; Nerve; Performance; Pregnancy; Pregnant Women; Purpose; Rattus; Research; Research Personnel; Resources; Source; Staging; Supplementation; United States National Institutes of Health; Woman; improved

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to determine if supplemental choline consumption has an effect on a pregnant woman by: 1) increasing the level of choline in the woman's blood, 2)increasing the level of choline in the woman's breast milk, 3) enhancing memory performance in her baby. Studies have shown that choline is a necessary part of the human diet. Choline is important in makin membranes for all the cells in the body, and for making chemicals that are responsible for nerve function. Studies have also shown that choline improves memory of rats when they are given choline at early stages in their lives. This study will show whether choline supplementation in pregnant women will improve memory function of their babies after they are born.

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 这项研究的目的是确定补充胆碱对孕妇是否有影响：1)增加妇女血液中的胆碱水平，2)增加妇女母乳中的胆碱水平，3)增强其婴儿的记忆能力。研究表明，胆碱是人类饮食中必不可少的一部分。胆碱在制造体内所有细胞的细胞膜以及制造负责神经功能的化学物质方面都很重要。研究还表明，当大鼠在生命的早期阶段给予胆碱时，胆碱可以改善它们的记忆。这项研究将展示孕妇补充胆碱是否会改善婴儿出生后的记忆功能。