CHOLINE, PREGNANCY, AND BRAIN DEVELOPMENT

该子项目是利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得主要资金， 因此可以在其他CRISP条目中表示。列出的机构是 中心，不一定是研究者的机构。 这项研究的目的是确定补充胆碱消费是否对孕妇有影响：1）增加妇女血液中的胆碱水平，2）增加妇女母乳中的胆碱水平，3）增强婴儿的记忆力。 研究表明，胆碱是人类饮食的必要组成部分。 胆碱在为身体的所有细胞制造膜和制造负责神经功能的化学物质方面很重要。 研究还表明，当大鼠在生命的早期阶段被给予胆碱时，胆碱可以改善它们的记忆力。 这项研究将显示孕妇补充胆碱是否会改善婴儿出生后的记忆功能。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to determine if supplemental choline consumption has an effect on a pregnant woman by: 1) increasing the level of choline in the woman's blood, 2)increasing the level of choline in the woman's breast milk, 3) enhancing memory performance in her baby. Studies have shown that choline is a necessary part of the human diet. Choline is important in makin membranes for all the cells in the body, and for making chemicals that are responsible for nerve function. Studies have also shown that choline improves memory of rats when they are given choline at early stages in their lives. This study will show whether choline supplementation in pregnant women will improve memory function of their babies after they are born.