Colorado Career Development Program in the Genetics and Genomics of Lung Diseases

认识到应用于人类疾病的遗传学和基因组学技术日益重要， 并意识到肺部疾病研究可以从这些技术的扩展使用中受益的程度， 技术，我们提出了科罗拉多肺遗传学和基因组学计划（CPGGP）， 肺遗传学和基因组学研究学者的职业发展。 拟议职业发展方案的目标： 培养肺部疾病遗传学和基因组学临床研究领域的领导者 建立一个课程，结合我们现有的最好的肺医学培训，人类医学 遗传学和临床科学课程 增加协作 从各种背景中招募优秀学者 我们提出的计划响应NHLBI蓝图，并有以下组成部分，以实现 这些目标： 一门课程，旨在使所有学者对基础知识有相应的理解， 肺病遗传学和基因组学研究的现实，无论其背景如何 通过在正在进行的遗传学和/或基因组学研究中的研究机会， 四大肺部疾病：急性肺损伤/急性呼吸窘迫综合征（ALI/ARDS）， 肺动脉高压（PH）、慢性阻塞性肺疾病/癌症预防（COPD/CA）、 和肉芽肿性肺病 通过共同指导的研究项目进行合作 通过临床研究设计、监管培训为独立临床研究做好准备 人类医学遗传学研究中的监督、拨款、人类受试者使用和固有伦理 方案评估和学员跟踪 该计划吸收了肺部疾病，医学遗传学，生物信息学， 和临床科学培训计划，以便为学者提供重要选择的机会 关于他们的旅程通过该计划，并优化他们未来的成功。在当前的范例中， 不仅学者将受益，导师也将通过参与该计划而受益。以上 广泛涵盖选定的肺部疾病，该计划可以对 遗传学和基因组学在肺部疾病中的应用。

In recognition of the growing importance of genetics and genomics techniques applied to human disease, and in awareness of the extent to which lung disease research could benefit from expanded use of these technologies, we propose the Colorado Pulmonary Genetics and Genomics Program (CPGGP) for the career development of scholars in pulmonary genetics and genomics research. Objectives of the proposed career development program: Train leaders in the field of clinical research in lung disease genetics and genomics Build a curriculum combining the best of our existing pulmonary medicine training, human medical genetics, and clinical sciences programs Increase collaboration Recruit excellent scholars from various backgrounds Our proposed program responds to the NHLBI blueprint and has the following components for achieving these objectives: A curriculum designed to bring all scholars to a commensurate understanding of the fundamentals and realities of lung disease genetics and genomics research, regardless of their background Breadth of study through research opportunities in ongoing genetics and/or genomics research in one of four major lung diseases: Acute Lung Injury / Acute Respiratory Distress Syndrome (ALI/ARDS), Pulmonary Hypertension (PH), Chronic Obstructive Pulmonary Disease / Cancer Prevention (COPD/CA), and Granulomatous Lung Disease Collaboration through co-mentored research projects Preparation for independent clinical research through training in clinical research design, regulatory oversight, grant writing, human subject use, and ethics inherent in human medical genetics research Program evaluation and trainee follow-up The Program assimilates the expertise resident in Pulmonary Diseases, Medical Genetics, Bioinformatics, and the Clinical Sciences Training Program in order to afford Scholars the opportunity for significant choices regarding their journey through the Program, and optimizing their future success. In the current paradigm, not only will Scholars benefit, but Mentors will also profit through their involvement in the Program. By more broadly covering selected Pulmonary Diseases, the Program can have a pronounced impact on the application of genetics and genomics to lung diseases.