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Environmental Influence on T-Cell Leukemia: Role of Notch and AhR Signaling

Environmental Influence on T-Cell Leukemia: Role of Notch and AhR Signaling
环境对 T 细胞白血病的影响：Notch 和 AhR 信号传导的作用
批准号：
8076899
负责人：
Michael D Laiosa
金额：
$24.9万
依托单位：
UNIVERSITY OF WISCONSIN MILWAUKEE
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
项目状态：
已结题
起止时间：
2010-06-01 至 2013-02-28
来源：
https://reporter.nih.gov/project-details/8076899
关键词：
Acute T Cell LeukemiaAdultAffectAgeApoptosisApoptoticAryl Hydrocarbon ReceptorBHLH ProteinBindingCancer EtiologyCell Cycle ProgressionCell Cycle RegulationCell LineageCell ProliferationChemicalsChildChildhoodChildhood LeukemiaComplexDNA biosynthesisDataDevelopmentDiagnosisDioxinsDiseaseDisease ProgressionElementsEnhancersEnvironmental ExposureEnvironmental PollutantsEnvironmental PollutionEnvironmental Risk FactorEpidemiologic StudiesExposure toGene ExpressionGene MutationGene TargetingGenesGeneticGenetic Predisposition to DiseaseGoalsHourHumanImmunotoxicologyIndividualKnowledgeLeadLeukemia in RemissionLifeLigandsLinkMalignant NeoplasmsMentorsMicroarray AnalysisModelingMusMutationOncogenicOrganPatientsPlayPopulationPositioning AttributeProgressive DiseaseProteinsPublic HealthReceptor ActivationRecurrenceRegulationRegulator GenesResearchResveratrolRoleSamplingScientistSignal TransductionStagingStimulusSurvival RateT-Cell DevelopmentT-Cell LeukemiaT-LymphocyteTestingTetrachlorodibenzodioxinThymocyte DevelopmentThymus GlandToxic effectTrainingTranslatingTreatment ProtocolsUnited StatesWorkagedbasecancer riskenvironmental agentexperiencegenetic regulatory proteingenetic risk factorimprovedleukemianotch proteinoutcome forecastpre-clinicalprenatal exposurepreventreceptor expressionresearch clinical testingself-renewalthymocyte

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Regulation of metabolism by the Aryl hydrocarbon receptor in hematopoietic and immune cell progenitors
  • 批准号：
    10353238
  • 项目类别：
  • 资助金额：
    $22.5万
  • 财政年份：
    2021
  • 负责人：
    Michael D Laiosa
  • 依托单位：
    UNIVERSITY OF WISCONSIN MILWAUKEE
Regulation of metabolism by the Aryl hydrocarbon receptor in hematopoietic and immune cell progenitors
  • 批准号：
    10538613
  • 项目类别：
  • 资助金额：
    $18.73万
  • 财政年份：
    2021
  • 负责人：
    Michael D Laiosa
  • 依托单位：
    UNIVERSITY OF WISCONSIN MILWAUKEE
Environmental Influence on T-Cell Leukemia: Role of Notch and AhR Signaling
Environmental Influence on T-Cell Leukemia: Role of Notch and AhR Signaling
  • 批准号：
    8265985
  • 项目类别：
  • 资助金额：
    $24.36万
  • 财政年份：
    2010
  • 负责人：
    Michael D Laiosa
  • 依托单位：
    UNIVERSITY OF WISCONSIN MILWAUKEE
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