Regulation of LKB1 and AMPK Signaling by BRAF in Melanoma
Regulation of LKB1 and AMPK Signaling by BRAF in Melanoma
批准号:
8106446
负责人:
Bin Zheng
金额:
$24.15万
依托单位国家:
美国
项目类别:
财政年份:
2008
资助国家:
美国
项目状态:
已结题
起止时间:
2008-06-01 至 2013-06-30
关键词:
3T3-L1 Cells5&apos-AMP-activated protein kinaseAMP-activated protein kinase kinaseAbateAcademic Medical CentersAdvisory CommitteesApoptosisAppointmentAreaBRAF geneBiochemicalBiological AssayCDK4 geneCI-1040Cancer BiologyCell Cycle ProgressionCell LineCell ProliferationCell SurvivalCellsClinical ResearchClinical TrialsCollaborationsCollectionCombined Modality TherapyComprehensive Cancer CenterDataDermatologyDoctor of PhilosophyDown-RegulationEnergy MetabolismEnvironmentEnzymesFamilyFatty AcidsFutureGene MutationGenesGenetic DeterminismGoalsGrantHumanIn VitroIncidenceInhibition of Cell ProliferationInstructionKnockout MiceLaboratoriesLightLinkMEKsMaintenanceMalignant - descriptorMalignant NeoplasmsMediatingMelaninsMelanoma CellMentorsMetabolicMetabolismMetforminModificationMolecularMusMutateMutationNeoplasm MetastasisOncogenicPTEN genePathogenesisPathway interactionsPatientsPeutz-Jeghers SyndromePhasePhase I Clinical TrialsPhosphorylationPhosphotransferasesPigmentsPlayProlineProtein BindingProtein KinaseProtein-Serine-Threonine KinasesProteinsProto-Oncogene Proteins B-rafPublicationsRNARegulationReportingResearchResistanceRoleSH3 DomainsSTK11 geneSU 6656SamplingSignal PathwaySignal TransductionSignaling ProteinSkin CancerSrc family kinase inhibitor PP2StressTSC2 geneTestingTherapeuticTimeLineTissue MicroarrayTumor Suppressor ProteinsUniversitiesWorkXenograft ModelXenograft procedureanalogbasecancer typecarcinogenesiscareercell growthdesigngenetic regulatory proteinglucose uptakein vivoinhibitor/antagonistinsightinterestmTOR Signaling Pathwaymedical schoolsmelanocytemelanomamembermolecular pathologymortalitymutantnoveloverexpressionoxidationpost-doctoral trainingpre-clinicalpreclinical studyresearch studyresponsesensorsrc-Family Kinasestherapeutic targettumortumor growthtumorigenesisuptake
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Administrative Core
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批准号:10334982
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项目类别:
-
资助金额:$64.25万
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财政年份:2022
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负责人:Bin Zheng
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依托单位:
Oklahoma Center of Medical Imaging for Translational Cancer Research
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批准号:10334981
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项目类别:
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资助金额:$228.64万
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财政年份:2022
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负责人:Bin Zheng
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依托单位:
Regulation of interferon signaling in melanoma by the cohesin complex protein STAG2 via 3D genome organization
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批准号:10905899
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项目类别:
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资助金额:$37.44万
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财政年份:2022
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负责人:Bin Zheng
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依托单位:
Targeting the LKB1-AMPK pathway in melanoma: Mechanism and preclinical evaluation
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批准号:9690391
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项目类别:
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资助金额:$7.5万
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财政年份:2012
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负责人:Bin Zheng
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依托单位:
Mammographic Density and Tissue Asymmetry Based Breast Cancer Risk Stratification
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批准号:8691598
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项目类别:
-
资助金额:$21.98万
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财政年份:2012
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负责人:Bin Zheng
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依托单位:
Targeting the LKB1-AMPK pathway in melanoma: Mechanism and preclinical evaluation
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批准号:8723596
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项目类别:
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资助金额:$28.12万
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财政年份:2012
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负责人:Bin Zheng
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依托单位:
Targeting the LKB1-AMPK PATHWAY in Melanoma: Mechanism and Preclinical Evaluation
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批准号:8466942
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项目类别:
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资助金额:$3.08万
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财政年份:2012
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负责人:Bin Zheng
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依托单位:
Mammographic Density and Tissue Asymmetry Based Breast Cancer Risk Stratification
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批准号:8826571
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项目类别:
-
资助金额:$22.68万
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财政年份:2012
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负责人:Bin Zheng
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依托单位:
Targeting the LKB1-AMPK pathway in melanoma: Mechanism and preclinical evaluation
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批准号:8657935
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项目类别:
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资助金额:$33.51万
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财政年份:2012
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负责人:Bin Zheng
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依托单位:
Mammographic Density and Tissue Asymmetry Based Breast Cancer Risk Stratification
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批准号:8282037
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项目类别:
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资助金额:$23.07万
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财政年份:2012
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负责人:Bin Zheng
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依托单位:
Targeting the LKB1-AMPK PATHWAY in Melanoma: Mechanism and Preclinical Evaluation
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批准号:8275994
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项目类别:
-
资助金额:$33.2万
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财政年份:2012
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负责人:Bin Zheng
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依托单位:
Regulation of LKB1 and AMPK Signaling by BRAF in Melanoma
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批准号:7450012
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项目类别:
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资助金额:$13.18万
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财政年份:2008
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负责人:Bin Zheng
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依托单位:
Regulation of LKB1 and AMPK Signaling by BRAF in Melanoma
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批准号:8301009
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项目类别:
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资助金额:$24.15万
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财政年份:2008
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负责人:Bin Zheng
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依托单位:
Regulation of LKB1 and AMPK Signaling by BRAF in Melanoma
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批准号:8068459
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项目类别:
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资助金额:$24.9万
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财政年份:2008
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负责人:Bin Zheng
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依托单位:
Regulation of LKB1 and AMPK Signaling by BRAF in Melanoma
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批准号:7619638
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项目类别:
-
资助金额:$13.2万
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财政年份:2008
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负责人:Bin Zheng
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依托单位:
Interactive CAD for Mammography
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批准号:6929774
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项目类别:
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资助金额:$16.84万
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财政年份:2004
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负责人:Bin Zheng
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依托单位:
Interactive CAD for Mammography
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批准号:6770917
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项目类别:
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资助金额:$16.86万
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财政年份:2004
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负责人:Bin Zheng
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依托单位:
Interactive CAD for Mammography
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批准号:7240502
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项目类别:
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资助金额:$16.36万
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财政年份:2004
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负责人:Bin Zheng
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依托单位:
Interactive CAD for Mammography
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批准号:7114983
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项目类别:
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资助金额:$16.85万
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财政年份:2004
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负责人:Bin Zheng
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依托单位:
CAD FOR EARLIER DETECTION OF BREAST CANCER
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批准号:6514382
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项目类别:
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资助金额:$14.96万
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财政年份:2001
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负责人:Bin Zheng
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依托单位:
国内基金
海外基金
晚期妊娠维持和抑制早产中cAMP信号活化PR的作用机制研究
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批准号:81300507
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项目类别:青年科学基金项目
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资助金额:22.0万元
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批准年份:2013
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负责人:陈黎
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依托单位: