UTPA - Cancer Center at UTHSCSA Border Partnership (1 of 2)

UTPA - UTHSCSA 边境合作癌症中心（1 of 2）

• 批准号: 7693675
• 负责人: Bimal K Banik
• 金额: $ 22.94万
• 依托单位: UNIVERSITY OF TEXAS RIO GRANDE VALLEY
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-09-26 至 2012-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7693675
• 关键词: Address; Affinity; American; Amides; Amines; Antineoplastic Agents; Apoptosis; Apoptotic; Aromatic Compounds; Attitude; Basic Science; Binding; Biological; Cancer Biology; Cancer Burden; Cancer Center; Cell Death; Cell Survival; Chrysenes; Clinical Trials; Communities; Decision Making; Education; Effectiveness; Electrons; Fostering; Genetic screening method; Goals; Health Sciences; Hispanics; Human; In Vitro; Laboratories; Latino; Lead; Learning; Malignant Neoplasms; Measures; Metabolism; Methods; Mexico; Minority; Mus; Natural Killer Cells; Normal tissue morphology; Pan Genus; Pathway interactions; Pilot Projects; Play; Population; Postdoctoral Fellow; Preparation; Process; Research; Research Personnel; Research Training; Role; Side; South Texas; Students; System; T-Lymphocyte; TdT-Mediated dUTP Nick End Labeling Assay; Testing; Texas; Toxic effect; Training; Training Programs; Translational Research; Tumor Cell Line; Universities; Work; alkalinity; analog; anticancer research; base; cancer risk; cancer therapy; caspase-3; graduate student; health disparity; in vivo; interest; leukemia; malignant breast neoplasm; programs; tumor

DESCRIPTION (provided by applicant): The Latino/Hispanic population is the largest minority in the US and the highest concentration of Latinos is along the US-Mexico Border. To address the specific needs of this population in cancer research and education, a partnership between The University of Texas-Pan American and the Cancer Center at The University of Texas Health Science Center at San Antonio is proposed. The goals of this application are to develop research and training partnerships to increase the cancer research base on the US-Mexico border. The projects proposed will not only develop translational research in basic science but also address cancer related health disparities in the Hispanic border population. The specific goals of the application are: 1. to develop and foster cancer research at UTPA; 2. to foster research dedicated towards reducing the cancer burden of the Hispanic population with emphasis on the US-Mexico border, and 3. to increase the number of cancer researchers coming from South Texas. To accomplish these goals, two pilot projects and a training program are proposed. The first pilot project is a basic science project which will take advantage of the expertise at UTPA to synthesize polycyclic aromatic compounds and expertise at UTHSCSA to test these compounds as anticancer agents. The second pilot project is directed toward understanding the attitudes and decision making processes in genetic testing for increased breast cancer risk. The third project is a summer undergraduate program for UTPA students to work in laboratories and to learn about cancer biology with the goal of increasing the number of students from communities in South Texas interested in cancer research. This multidimensional approach will heighten cancer research and education in the Hispanic/Latino population along the Texas border.

描述（由申请人提供）：拉丁裔/西班牙裔人口是美国最大的少数民族，而拉丁美洲人的最高集中在美国 - 墨西哥边境沿线。为了满足该人群在癌症研究和教育方面的特定需求，提议提议得克萨斯大学美国大学与德克萨斯大学健康科学中心的癌症中心之间的伙伴关系。该应用程序的目标是开发研究和培训伙伴关系，以提高美墨边境的癌症研究基础。拟议的项目不仅将在基础科学领域发展转化研究，而且还将解决西班牙裔边境人口中与癌症相关的健康差异。该应用程序的具体目标是：1。在UTPA开发和促进癌症研究； 2。促进研究致力于减轻西班牙裔人口的癌症负担，重点是美墨边境，3。增加来自南德克萨斯州的癌症研究人员的数量。为了实现这些目标，提出了两个试点项目和一个培训计划。第一个试点项目是一个基础科学项目，该项目将利用UTPA的专业知识来合成UTHSCSA的多环化合物和专业知识，以测试这些化合物作为抗癌剂。第二个试点项目旨在理解基因检测中乳腺癌风险增加的态度和决策过程。第三个项目是一项夏季本科课程，供UTPA学生从事实验室工作并了解癌症生物学，以增加对癌症研究感兴趣的南德克萨斯州社区的学生人数。这种多维方法将加强德克萨斯州边境西班牙裔/拉丁裔人口的癌症研究和教育。