IN VITRO AND IN VIVO CHARACTERIZATION OF THE NOVEL BENZODIAZEPINE ANALOG NEP-510

新型苯二氮卓类似物 NEP-510 的体外和体内表征

• 批准号: 7958377
• 负责人: JAMES K ROWLETT
• 金额: $ 1.27万
• 依托单位: HARVARD MEDICAL SCHOOL
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-05-01 至 2010-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7958377
• 关键词: Agonist; Anti-Anxiety Agents; Benzodiazepines; Computer Retrieval of Information on Scientific Projects Database; Funding; GABA-A Receptor; Grant; In Vitro; Institution; Macaca mulatta; New England; Primates; Research; Research Personnel; Resources; Source; United States National Institutes of Health; analog; base; in vivo; novel; sedative

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The GABA-A receptor agonist NEP-510 was shown to have agonist activity at alpha2- and alpha 3-subunit containing GABA-A receptors; and to have anxiolytic- and sedative-like effects in rhesus monkeys.

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