REGULATION OF INNATE IMMUNITY TO ENTEROCYTOZOON BIENEUSI INFECTION

对肠细胞虫感染的先天免疫的调节

• 批准号: 7958373
• 负责人: SAUL r TZIPORI
• 金额: $ 11.19万
• 依托单位: HARVARD MEDICAL SCHOOL
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-05-01 至 2010-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7958373
• 关键词: Animals; Computer Retrieval of Information on Scientific Projects Database; Enterocytozoon bieneusi; Feces; Funding; Grant; Human; Immune response; In Vitro; Infection; Institution; Investigation; Laboratories; Macaca mulatta; Natural Immunity; New England; Primates; Regulation; Reproduction spores; Research; Research Personnel; Resources; Source; United States National Institutes of Health; base; in vivo

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The feces were collected from SIV-infected animals and were analyzed for the presence of Eb spores from which they were purified for laboratory investigations: 1) Comparison of Enterocytozoon bieneusi from Human and Rhesus macaque: Similarities and Differences; 2) Characterization of the innate immune responses in vitro or in vivo to the purified Eb spores.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 从SIV感染的动物收集粪便并分析Eb孢子的存在，从中纯化它们用于实验室研究：1）来自人和恒河猴的比氏肠细胞虫的比较：相似性和差异; 2）对纯化的Eb孢子的体外或体内先天免疫应答的表征。