SPECIES-SPECIFICITY OF HIV-1 AND SIV IN OVERCOMING RESTRICTION BY TETHERIN/BST2
SPECIES-SPECIFICITY OF HIV-1 AND SIV IN OVERCOMING RESTRICTION BY TETHERIN/BST2
批准号:
7958383
负责人:
David T Evans
金额:
$20.61万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2009
资助国家:
美国
项目状态:
已结题
起止时间:
2009-05-01 至 2010-04-30
中文摘要
这个子项目是许多研究子项目中的一个
由NIH/NCRR资助的中心赠款提供的资源。子项目和
研究者(PI)可能从另一个NIH来源获得了主要资金,
因此可以在其他CRISP条目中表示。所列机构为
研究中心,而研究中心不一定是研究者所在的机构。
这项研究确定了SIV的基因产物,在恒河猴中对抗Tetherin,并确定了人类和恒河猴Tetherin之间的差异,这些差异导致了HIV-1和SIV的物种特异性限制。
英文摘要
This subproject is one of many research subprojects utilizing the
resources provided by a Center grant funded by NIH/NCRR. The subproject and
investigator (PI) may have received primary funding from another NIH source,
and thus could be represented in other CRISP entries. The institution listed is
for the Center, which is not necessarily the institution for the investigator.
This study identified the gene product of SIV that opposes tetherin in rhesus macaques and defined the differences between human and rhesus tetherin that account for species-specific restriction of HIV-1 and SIV.
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会议论文
Evaluation of didehydro-Cortistatin A as a block-and-lock agent for a functional HIV cure in a macaque model
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批准号:10403162
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项目类别:
-
资助金额:$44.11万
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财政年份:2021
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负责人:David T Evans
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依托单位:
Evaluation of didehydro-Cortistatin A as a block-and-lock agent for a functional HIV cure in a macaque model
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批准号:10591883
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项目类别:
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资助金额:$45.09万
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财政年份:2021
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负责人:David T Evans
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依托单位:
Tethering lentiviral restriction to Fc-mediated antibody responses
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批准号:10425358
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项目类别:
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资助金额:$70.77万
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财政年份:2020
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负责人:David T Evans
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依托单位:
Tethering lentiviral restriction to Fc-mediated antibody responses
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批准号:10082732
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项目类别:
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资助金额:$45.44万
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财政年份:2020
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负责人:David T Evans
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依托单位:
Tethering lentiviral restriction to Fc-mediated antibody responses
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批准号:10203816
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项目类别:
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资助金额:$45.58万
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财政年份:2020
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负责人:David T Evans
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依托单位:
Tethering lentiviral restriction to Fc-mediated antibody responses
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批准号:10661036
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项目类别:
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资助金额:$77.6万
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财政年份:2020
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负责人:David T Evans
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依托单位:
Assessing ADCC and Fc-mediated Protection against HIV
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批准号:10671615
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项目类别:
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资助金额:$76.71万
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财政年份:2019
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负责人:David T Evans
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依托单位:
Assessing ADCC and Fc-mediated Protection against HIV
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批准号:10808458
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项目类别:
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资助金额:$18.56万
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财政年份:2019
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负责人:David T Evans
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依托单位:
Assessing ADCC and Fc-mediated Protection against HIV
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批准号:10226317
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项目类别:
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资助金额:$76.5万
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财政年份:2019
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负责人:David T Evans
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依托单位:
Assessing ADCC and Fc-mediated Protection against HIV
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批准号:10458659
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项目类别:
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资助金额:$76.76万
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财政年份:2019
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负责人:David T Evans
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依托单位:
Fcgamma receptor-mediated suppression of immunodeficiency virus replication
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批准号:9275920
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项目类别:
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资助金额:$76.52万
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财政年份:2015
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负责人:David T Evans
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依托单位:
Lentiviral Resistance to Tetherin
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批准号:8790734
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项目类别:
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资助金额:$43.24万
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财政年份:2012
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负责人:David T Evans
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依托单位:
Lentiviral Resistance to Tetherin
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批准号:8415838
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项目类别:
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资助金额:$14.36万
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财政年份:2012
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负责人:David T Evans
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依托单位:
Lentiviral Resistance to Tetherin
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批准号:8604135
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项目类别:
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资助金额:$51.02万
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财政年份:2012
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负责人:David T Evans
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依托单位:
Lentiviral Resistance to Tetherin
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批准号:8326887
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项目类别:
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资助金额:$43.75万
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财政年份:2012
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负责人:David T Evans
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依托单位:
Lentiviral Resistance to Tetherin
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批准号:8894969
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项目类别:
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资助金额:$3.39万
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财政年份:2012
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负责人:David T Evans
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依托单位:
Lentiviral Resistance to Tetherin
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批准号:8717000
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项目类别:
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资助金额:$23.02万
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财政年份:2012
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负责人:David T Evans
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依托单位:
A NOVEL ASSAY FOR ANTIBODY-DEPENDENT CELL-MEDIATED CYTOTOXICITY
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批准号:8357976
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项目类别:
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资助金额:$21.06万
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财政年份:2011
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负责人:David T Evans
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依托单位:
KIR and MHC Class I Immunogenetics in SIV Infection
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批准号:10054150
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项目类别:
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资助金额:$70.42万
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财政年份:2011
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负责人:David T Evans
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依托单位:
KIR and MHC Class I Immunogenetics in SIV Infection
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批准号:10295770
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项目类别:
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资助金额:$70.71万
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财政年份:2011
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负责人:David T Evans
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依托单位: